FBXO44 and NPHP4

Data Source:
BioGRID (two hybrid)

		FBXO44	NPHP4
Description		F-box protein 44	nephrocystin 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex	Nucleoplasm Centrosome Cytosol Cell-cell Junction Bicellular Tight Junction Nuclear Body Ciliary Transition Zone Ciliary Basal Body Intracellular Membrane-bounded Organelle Ribbon Synapse Ciliary Base Non-motile Cilium Photoreceptor Distal Connecting Cilium
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity	Structural Molecule Activity Protein Binding
	Biological Process	Protein Polyubiquitination Glycoprotein Catabolic Process Proteasomal Protein Catabolic Process Ubiquitin-dependent ERAD Pathway SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification	Signal Transduction Visual Behavior Actin Cytoskeleton Organization Flagellated Sperm Motility Hippo Signaling Photoreceptor Cell Outer Segment Organization Photoreceptor Cell Maintenance Retina Development In Camera-type Eye Negative Regulation Of Canonical Wnt Signaling Pathway Ciliary Basal Body-plasma Membrane Docking Cell-cell Adhesion Positive Regulation Of Bicellular Tight Junction Assembly Protein Localization To Ciliary Transition Zone
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Signaling by Hippo Anchoring of the basal body to the plasma membrane
Drugs
Diseases			Senior-Loken syndrome Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
GWAS		Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Neurological blood protein biomarker levels ( 31320639)	Dimensional psychopathology (Positive) ( 29496196) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) QT interval ( 19305408) Response to taxane treatment (placlitaxel) ( 23006423)
Interacting Genes		12 interacting genes: BLOC1S1 BORCS6 BRCA1 C11orf45 HSF2BP ISY1-RAB43 MEOX2 PRDM5 SERTAD3 SKP1 SPG21 UBC	2 interacting genes: NPHP1 RPGRIP1
Entrez ID		93611	261734
HPRD ID		16445	06238
Ensembl ID		ENSG00000132879	ENSG00000131697
Uniprot IDs		A0A024R4F9 A0A024R4J6 B7Z1P2 Q9H4M3	B3KW36 O75161
PDB IDs		3WSO 5B4N
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?