LONP1 and LOXL4

Data Source:
BioGRID (two hybrid)

		LONP1	LOXL4
Description		lon peptidase 1, mitochondrial	lysyl oxidase like 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol Membrane Mitochondrial Nucleoid	Extracellular Space Membrane Receptor Complex Extracellular Exosome
	Molecular Function	Mitochondrial Promoter Sequence-specific DNA Binding Single-stranded DNA Binding Single-stranded RNA Binding ATP-dependent Peptidase Activity Serine-type Endopeptidase Activity Protein Binding ATP Binding ATPase Activity Identical Protein Binding ADP Binding Sequence-specific DNA Binding G-quadruplex DNA Binding DNA Polymerase Binding	Protein-lysine 6-oxidase Activity Scavenger Receptor Activity Copper Ion Binding Protein Binding
	Biological Process	Mitochondrial Genome Maintenance Response To Hypoxia Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Mitochondrion Organization Aging Response To Hormone Response To Aluminum Ion Mitochondrial DNA Metabolic Process Cellular Response To Oxidative Stress Chaperone-mediated Protein Complex Assembly Proteolysis Involved In Cellular Protein Catabolic Process Oxidation-dependent Protein Catabolic Process	Endocytosis Peptidyl-lysine Oxidation Protein Phosphopantetheinylation Collagen Fibril Organization
Pathways			Elastic fibre formation Crosslinking of collagen fibrils
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494)	Body mass index ( 29273807) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Height ( 31562340) Multiple system atrophy ( 27629089)
Interacting Genes		11 interacting genes: A2M APOE CDC37 CDC42 CYP2C8 ECSIT IFIT3 IFIT5 LOXL4 MAST1 RNF32	15 interacting genes: AP1M2 APOE CDC37 COL2A1 ECSIT EXOC6 KDM1A LONP1 MAST1 MTDH PRMT6 RAD23A RNF32 SUV39H1 TRIP13
Entrez ID		9361	84171
HPRD ID		05689	09538
Ensembl ID		ENSG00000196365	ENSG00000138131
Uniprot IDs		P36776	Q96JB6
PDB IDs		2X36
Enriched GO Terms of Interacting Partners?
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