GTF3C2 and GTF3C4

Data Source:
HPRD (in vivo, in vitro)

		GTF3C2	GTF3C4
Description		general transcription factor IIIC subunit 2	general transcription factor IIIC subunit 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Transcription Factor TFIIIC Complex Nucleoplasm	Transcription Factor TFIIIC Complex Nucleoplasm Mitochondrion
	Molecular Function	DNA Binding Protein Binding	DNA Binding Histone Acetyltransferase Activity Protein Binding Enzyme Activator Activity
	Biological Process	Transcription By RNA Polymerase III 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III	Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter Histone Acetylation 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III Regulation Of Catalytic Activity
Pathways		RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS		Menopause (age at onset) ( 26414677) Metabolite levels ( 23823483) Urinary albumin-to-creatinine ratio ( 32600054)
Interacting Genes		8 interacting genes: GRIA2 GTF3A GTF3C4 PTEN RB1 SUMO2 TBP VAC14	13 interacting genes: AURKA BRCA1 BRF1 GTF3C1 GTF3C2 GTF3C5 GTF3C6 H3-4 H3C15 POLR3C POLR3F SUMO2 TBP
Entrez ID		2976	9329
HPRD ID		05347	11998
Ensembl ID		ENSG00000115207	ENSG00000125484
Uniprot IDs		Q8WUA4	B3KNH2 Q9UKN8
PDB IDs
Enriched GO Terms of Interacting Partners?
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