DTD1 and PTPA

Data Source:
BioGRID (enzymatic study)

		DTD1	PTPA
Description		D-aminoacyl-tRNA deacylase 1	protein phosphatase 2 phosphatase activator
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GO Annotations	Cellular Component	Nucleus Cytoplasm	Protein Phosphatase Type 2A Complex Nucleus Nucleoplasm Cytoplasm Calcium Channel Complex Extracellular Exosome
	Molecular Function	TRNA Binding DNA Binding Metal Ion Binding D-tyrosyl-tRNA(Tyr) Deacylase Activity	Peptidyl-prolyl Cis-trans Isomerase Activity Signaling Receptor Binding Protein Binding ATP Binding Protein Tyrosine Phosphatase Activator Activity ATPase Activity Protein Phosphatase Regulator Activity Protein Homodimerization Activity Protein Phosphatase 2A Binding
	Biological Process	DNA Replication TRNA Metabolic Process Aminoacyl-tRNA Metabolism Involved In Translational Fidelity	Protein Peptidyl-prolyl Isomerization Mitotic Spindle Organization Negative Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Protein Dephosphorylation Positive Regulation Of Apoptotic Process Regulation Of Phosphoprotein Phosphatase Activity
Pathways
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30679032) Bitter alcoholic beverage consumption ( 31046077) C-reactive protein (red blood cell fatty acid level interaction) ( 28820441) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		4 interacting genes: CDC7 CSNK2A1 NR3C1 PTPA	28 interacting genes: AKT1 AMOT APP AURKB CCDC125 CCNE1 CCNG1 CCNG2 CSNK2A1 CYLD DTD1 EIF4EBP1 F3 FOXO3 GRIN3A H2AX HDAC4 KISS1R MAPT MID1 NIF3L1 PPP2R1A PPP2R3A PRKCB RACGAP1 SPG21 SRC SULT4A1
Entrez ID		92675	5524
HPRD ID		13631	02858
Ensembl ID		ENSG00000125821	ENSG00000119383
Uniprot IDs		A0A2R8Y6X2 Q8TEA8	B4DZF8 F6WIT2 Q15257
PDB IDs		2OKV	2G62 2HV6 2HV7 2IXM 4LAC 4NY3
Enriched GO Terms of Interacting Partners?
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