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CD7 and CTSL
Data Source:
HPRD
(in vivo)
CD7
CTSL
Description
CD7 molecule
cathepsin L
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Membrane
Integral Component Of Membrane
Extracellular Region
Extracellular Space
Nucleus
Lysosome
Multivesicular Body
Golgi Apparatus
Plasma Membrane
Apical Plasma Membrane
Endolysosome Lumen
Chromaffin Granule
Lysosomal Lumen
Intracellular Membrane-bounded Organelle
Collagen-containing Extracellular Matrix
Extracellular Exosome
Molecular Function
Protein Binding
Signaling Receptor Activity
Fibronectin Binding
Cysteine-type Endopeptidase Activity
Protein Binding
Collagen Binding
Cysteine-type Peptidase Activity
Histone Binding
Proteoglycan Binding
Serpin Family Protein Binding
Biological Process
Adaptive Immune Response
Immune Response
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
T Cell Activation
Toll-like Receptor Signaling Pathway
Adaptive Immune Response
Proteolysis
Immune Response
Protein Autoprocessing
Fusion Of Virus Membrane With Host Plasma Membrane
Receptor-mediated Endocytosis Of Virus By Host Cell
Antigen Processing And Presentation
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Extracellular Matrix Disassembly
Collagen Catabolic Process
Zymogen Activation
Enkephalin Processing
Fusion Of Virus Membrane With Host Endosome Membrane
CD4-positive, Alpha-beta T Cell Lineage Commitment
Regulation Of Keratinocyte Differentiation
Viral Entry Into Host Cell
Antigen Processing And Presentation Of Peptide Antigen
Proteolysis Involved In Cellular Protein Catabolic Process
Elastin Catabolic Process
Macrophage Apoptotic Process
Cellular Response To Thyroid Hormone Stimulus
Pathways
Endosomal/Vacuolar pathway
Collagen degradation
Degradation of the extracellular matrix
Trafficking and processing of endosomal TLR
Assembly of collagen fibrils and other multimeric structures
MHC class II antigen presentation
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
Attachment and Entry
Attachment and Entry
Attachment and Entry
Drugs
L-cysteic acid
Felbinac
Fostamatinib
Diseases
GWAS
Blood protein levels (
30072576
)
Interacting Genes
9 interacting genes:
CPTP
CTSL
LGALS1
NFKBIA
PI4KA
PIK3R1
SEC22A
SECTM1
SNAP29
28 interacting genes:
ARSA
BAG6
BTN3A3
CD7
CD74
COL18A1
CST3
CST7
CSTA
CSTB
CTSC
CUX1
CXCL8
EED
GCG
GEM
IGFBP3
KNG1
MCPH1
PLAU
PPP1CC
RELB
RXRA
SERPINB13
SERPINB3
SGTA
SLPI
TG
Entrez ID
924
1514
HPRD ID
01732
00293
Ensembl ID
ENSG00000173762
ENSG00000135047
Uniprot IDs
J3QLC7
P09564
Q29VG3
A0A024R276
P07711
Q9HBQ7
PDB IDs
1CJL
1CS8
1ICF
1MHW
2NQD
2VHS
2XU1
2XU3
2XU4
2XU5
2YJ2
2YJ8
2YJ9
2YJB
2YJC
3BC3
3H89
3H8B
3H8C
3HHA
3HWN
3IV2
3K24
3KSE
3OF8
3OF9
4AXL
4AXM
5F02
5I4H
5MAE
5MAJ
5MQY
6EZP
6EZX
6F06
6JD0
6JD8
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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