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DDX21 and MIR19A
Data Source:
BioGRID
(unspecified method)
DDX21
MIR19A
Description
DExD-box helicase 21
microRNA 19a
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Chromosome
Nucleolus
Mitochondrion
Cytosol
Membrane
Extracellular Space
Extracellular Exosome
Extracellular Vesicle
Molecular Function
RNA Binding
RNA Helicase Activity
Double-stranded RNA Binding
Protein Binding
ATP Binding
RRNA Binding
SnoRNA Binding
MiRNA Binding
Identical Protein Binding
7SK SnRNA Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
Osteoblast Differentiation
Positive Regulation Of Myeloid Dendritic Cell Cytokine Production
RRNA Processing
Transcription By RNA Polymerase II
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Response To Exogenous DsRNA
Innate Immune Response
Positive Regulation Of Gene Expression, Epigenetic
Defense Response To Virus
R-loop Disassembly
Negative Regulation Of Inflammatory Response To Antigenic Stimulus
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of Toll-like Receptor Signaling Pathway
Gene Silencing By MiRNA
B Cell Activation
Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
Negative Regulation Of Apoptotic Process
Negative Regulation Of Inflammatory Response
Positive Regulation Of B Cell Receptor Signaling Pathway
Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development
Cellular Response To Bacterial Lipopeptide
Negative Regulation Of Oxidative Stress-induced Cell Death
Negative Regulation Of Sprouting Angiogenesis
Regulation Of Cardiac Conduction
Negative Regulation Of Matrix Metallopeptidase Secretion
Pathways
B-WICH complex positively regulates rRNA expression
Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS
Depression (quantitative trait) (
20800221
)
Interacting Genes
87 interacting genes:
CALM1
CSNK2A1
DUX4
ERG
H2AX
IL7R
JUN
KPNA3
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
PIAS1
PTEN
SRPK2
SUMO2
TERF1
TERF2
UBE2I
99 interacting genes:
AGO2
AIMP2
APOBEC3B
ATXN2L
C1QBP
CELF1
CELF2
CPSF1
CPSF2
CPSF3
CPSF4
CPSF6
CPSF7
CRTAP
CSTF2
CSTF3
DARS1
DDX1
DDX21
DDX3X
DHX36
EIF2AK2
EPRS1
ERAL1
FAM98A
FIP1L1
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LIN28A
LRPPRC
MARS1
MATR3
MSI1
MSI2
NOL6
NONO
NUDT21
NUFIP2
P3H1
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PURA
QARS1
RARS1
RBBP6
RBFOX2
RBM12B
RBM14
RBM4
RBMS2
RTCB
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SUGP2
SYMPK
SYNCRIP
TAF15
TRA2A
TRA2B
U2SURP
UPF1
UTP20
WDR33
WWP1
WWP2
YBX1
YBX2
YBX3
ZFR
ZNF346
ZNF385A
Entrez ID
9188
406979
HPRD ID
05895
Ensembl ID
ENSG00000165732
ENSG00000284204
Uniprot IDs
Q9NR30
PDB IDs
2M3D
6L5L
6L5M
6L5N
6L5O
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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