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MIR19A and CPSF2
Data Source:
BioGRID
(unspecified method)
MIR19A
CPSF2
Description
microRNA 19a
cleavage and polyadenylation specific factor 2
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Extracellular Exosome
Extracellular Vesicle
Nucleoplasm
MRNA Cleavage And Polyadenylation Specificity Factor Complex
Membrane
Molecular Function
MRNA Binding Involved In Posttranscriptional Gene Silencing
RNA Binding
Protein Binding
Biological Process
Negative Regulation Of Inflammatory Response To Antigenic Stimulus
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of Toll-like Receptor Signaling Pathway
Gene Silencing By MiRNA
B Cell Activation
Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
Negative Regulation Of Apoptotic Process
Negative Regulation Of Inflammatory Response
Positive Regulation Of B Cell Receptor Signaling Pathway
Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development
Cellular Response To Bacterial Lipopeptide
Negative Regulation Of Oxidative Stress-induced Cell Death
Negative Regulation Of Sprouting Angiogenesis
Regulation Of Cardiac Conduction
Negative Regulation Of Matrix Metallopeptidase Secretion
MRNA Splicing, Via Spliceosome
Termination Of RNA Polymerase II Transcription
MRNA Polyadenylation
MRNA 3'-end Processing By Stem-loop Binding And Cleavage
MRNA Export From Nucleus
MRNA 3'-end Processing
Pre-mRNA Cleavage Required For Polyadenylation
Pathways
Transport of Mature mRNA Derived from an Intronless Transcript
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
3-month functional outcome in lacunar ischaemic stroke (modified Rankin score) (
30796134
)
B cell acute lymphoblastic leukaemia (hyperdiploid negative) (
29296818
)
B cell acute lymphoblastic leukaemia (normal cytogenetics) (
29296818
)
B cell acute lymphoblastic leukaemia (Philadelphia chromosome negative) (
29296818
)
Dialysis-related mortality (
21546767
)
Height (
18391951
)
LDL cholesterol levels x loop diuretics use interaction (
31806883
)
Monobrow (
27182965
)
Myopia (
27182965
)
Obesity-related traits (
23251661
)
Refractive error (
32231278
)
Interacting Genes
99 interacting genes:
AGO2
AIMP2
APOBEC3B
ATXN2L
C1QBP
CELF1
CELF2
CPSF1
CPSF2
CPSF3
CPSF4
CPSF6
CPSF7
CRTAP
CSTF2
CSTF3
DARS1
DDX1
DDX21
DDX3X
DHX36
EIF2AK2
EPRS1
ERAL1
FAM98A
FIP1L1
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LIN28A
LRPPRC
MARS1
MATR3
MSI1
MSI2
NOL6
NONO
NUDT21
NUFIP2
P3H1
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PURA
QARS1
RARS1
RBBP6
RBFOX2
RBM12B
RBM14
RBM4
RBMS2
RTCB
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SUGP2
SYMPK
SYNCRIP
TAF15
TRA2A
TRA2B
U2SURP
UPF1
UTP20
WDR33
WWP1
WWP2
YBX1
YBX2
YBX3
ZFR
ZNF346
ZNF385A
10 interacting genes:
MIR19A
MIR19B1
MIR92A1
MIR92A2
MIRLET7A1
MIRLET7A3
MIRLET7F2
POLR2A
SUMO2
WWOX
Entrez ID
406979
53981
HPRD ID
05824
Ensembl ID
ENSG00000284204
ENSG00000165934
Uniprot IDs
A0A024R6H0
Q9P2I0
PDB IDs
6URG
6V4X
Enriched GO Terms of Interacting Partners
?
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Tagcloud (Intersection)
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