NEK9 and NEK7

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		NEK9	NEK7
Description		NIMA related kinase 9	NIMA related kinase 7
Image
GO Annotations	Cellular Component	Nucleus Centrosome Cytosol	Spindle Pole Nucleoplasm Cytoplasm Microtubule Organizing Center Microtubule
	Molecular Function	Protein Binding ATP Binding Protein Kinase Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Protein Phosphorylation Mitotic Nuclear Envelope Disassembly Cell Division	Protein Phosphorylation Regulation Of Mitotic Cell Cycle Positive Regulation Of Telomere Maintenance Via Telomerase Spindle Assembly Positive Regulation Of Telomerase Activity Positive Regulation Of Telomere Capping
Pathways		Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation	Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation
Drugs		Fostamatinib
Diseases
GWAS		Coronary artery disease ( 29212778) Feeling fed-up ( 29500382)	Height ( 28552196) High altitude adaptation ( 28373541)
Interacting Genes		10 interacting genes: BICD2 CSN2 MBP NEK6 NEK7 NEK8 RAN SSRP1 SUPT16H TTN	2 interacting genes: NEK9 TERF1
Entrez ID		91754	140609
HPRD ID		11386	06027
Ensembl ID		ENSG00000119638	ENSG00000151414
Uniprot IDs		Q6PKF2 Q8TD19	B2R8K8 Q8TDX7
PDB IDs		3ZKE 3ZKF	2WQM 2WQN 5DE2 6NPY 6S73 6S75 6S76
Enriched GO Terms of Interacting Partners?
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