ZNF830 and PRPF8

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		ZNF830	PRPF8
Description		zinc finger protein 830	pre-mRNA processing factor 8
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Chromosome Nuclear Speck	Nucleus Nucleoplasm U5 SnRNP Membrane Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Nucleic Acid Binding Protein Binding Zinc Ion Binding	RNA Binding Protein Binding Metallopeptidase Activity U6 SnRNA Binding U1 SnRNA Binding U2 SnRNA Binding U5 SnRNA Binding Isopeptidase Activity K63-linked Polyubiquitin Modification-dependent Protein Binding Pre-mRNA Intronic Binding
	Biological Process	Ovarian Follicle Development Preantral Ovarian Follicle Growth Blastocyst Growth Transcription-coupled Nucleotide-excision Repair MRNA Processing RNA Splicing Nuclear DNA Replication Mitotic DNA Replication Checkpoint Negative Regulation Of Apoptotic Process Mitotic DNA Damage Checkpoint Replication Fork Protection Chromosome Organization Cell Division Intestinal Epithelial Structure Maintenance	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing Proteolysis RNA Splicing Cellular Response To Lipopolysaccharide Cellular Response To Tumor Necrosis Factor
Pathways		Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS		Night sleep phenotypes ( 27126917)	Blood protein levels ( 28240269) Calcium levels ( 20705733) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Ischemic stroke ( 29531354) Stroke ( 29531354)
Interacting Genes		7 interacting genes: FRA10AC1 ILF3 PCBP1 PRPF8 RAB4A SESTD1 THOC5	21 interacting genes: ABCA1 DHX9 DUX4 ERG GPKOW H2BC5 HNRNPH2 NEDD4 PIN1 PRPF19 PTEN RNF20 SERPINB2 SLC22A2 SND1 SNRNP200 SUMO2 TP53 UBC UBE2I ZNF830
Entrez ID		91603	10594
HPRD ID		14469	06295
Ensembl ID		ENSG00000198783	ENSG00000174231
Uniprot IDs		Q96NB3	Q6P2Q9
PDB IDs			3E9L 3ENB 3JCR 3LRU 4JK7 4JK8 4JK9 4JKA 4JKB 4JKC 4JKD 4JKE 4JKF 4JKG 4JKH 4KIT 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6S8Q 6S9I 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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