UBXN11 and RND3

Data Source:
HPRD (two hybrid, in vitro)

		UBXN11	RND3
Description		UBX domain protein 11	Rho family GTPase 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton	Golgi Membrane Cytoskeleton Plasma Membrane Focal Adhesion Cell Cortex Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Ubiquitin Binding	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Actin Filament Organization Cell Adhesion Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Cell Migration Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization
Pathways
Drugs			Guanosine-5'-Triphosphate
Diseases
GWAS		Monocyte percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Platelet count ( 32888494)	Arterial stiffness (brachial-ankle pulse wave velocity) ( 32790701) Endometriosis ( 23472165) Esophageal adenocarcinoma x gastroesophageal reflux disease interaction ( 29551738) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Neonatal total 25-hydroxyvitamin D levels (fetal genetic effect) ( 32047095) Platelet count ( 31217584) Reticulocyte fraction of red cells ( 32888494) Type 2 diabetes ( 22238593) Urinary metabolite levels in chronic kidney disease ( 29545352)
Interacting Genes		34 interacting genes: C14orf119 CFAP206 EIF4E EIF4E2 ENKD1 HGS IL16 LENG1 NEK6 PPM1K PRKAA1 PRKAB2 PRPF18 PRPF31 PRR35 PSMA1 RHOBTB3 RND1 RND2 RND3 RNF213 SCNM1 SH2D4A SNRPB TCEANC TLE5 TRAF2 TTC23 USHBP1 VCP VPS9D1 WDR25 ZFYVE9 ZGPAT	8 interacting genes: ARHGAP5 C14orf119 CIT CPLANE2 PLXNB1 ROCK1 SKP2 UBXN11
Entrez ID		91544	390
HPRD ID		10245	04233
Ensembl ID		ENSG00000158062	ENSG00000115963
Uniprot IDs		Q5T124	B2R838 P61587
PDB IDs			1M7B 2V55 4BG6
Enriched GO Terms of Interacting Partners?
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