RND3 and ROCK1

  • Data Source:
  • BioGRID (pull down)
  • HPRD (in vitro, in vivo, two hybrid)

RND3

ROCK1

Description Rho family GTPase 3 Rho associated coiled-coil containing protein kinase 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Arterial stiffness (brachial-ankle pulse wave velocity) ( 32790701)
  • Endometriosis ( 23472165)
  • Esophageal adenocarcinoma x gastroesophageal reflux disease interaction ( 29551738)
  • High light scatter reticulocyte count ( 32888494)
  • High light scatter reticulocyte percentage of red cells ( 32888494)
  • Immature fraction of reticulocytes ( 32888494)
  • Neonatal total 25-hydroxyvitamin D levels (fetal genetic effect) ( 32047095)
  • Platelet count ( 31217584)
  • Reticulocyte fraction of red cells ( 32888494)
  • Type 2 diabetes ( 22238593)
  • Urinary metabolite levels in chronic kidney disease ( 29545352)
  • Asthma exacerbations in inhaled corticosteroid treatment ( 30697902)
  • Lysophosphatidylcholine levels ( 31551469)
  • Telomere length ( 30185882)
Interacting Genes 8 interacting genes: ARHGAP5 C14orf119 CIT CPLANE2 PLXNB1 ROCK1 SKP2 UBXN11 36 interacting genes: ADD1 ARHGAP24 CASP3 CASP7 CDC25A CDC34 CFAP206 CRMP1 DES DPYSL2 EZR FAM124A GFAP IKBKB IRS1 ITSN2 LIMK1 LIMK2 LMO2 MAGEB4 MLC1 MSN PFN2 POLR3C PPP1R12A PTK2 RDX RHOA RHOC RND3 SMAD2 TPPP TRIM15 TSG101 UBE2T VIM
Entrez ID 390 6093
HPRD ID 04233 03414
Ensembl ID ENSG00000115963 ENSG00000067900
Uniprot IDs B2R838 P61587 Q13464
PDB IDs 1M7B 2V55 4BG6 1S1C 2ESM 2ETK 2ETR 2V55 3D9V 3NCZ 3NDM 3O0Z 3TV7 3TWJ 3V8S 4L2W 4W7P 4YVC 4YVE 5BML 5F5P 5HVU 5KKS 5KKT 5UZJ 5WNE 5WNF 5WNG 5WNH 6E9W 7JOU
Enriched GO Terms of Interacting Partners?
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