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AIFM1 and DCAF7
Data Source:
BioGRID
(fluorescent resonance energy transfer)
AIFM1
DCAF7
Description
apoptosis inducing factor mitochondria associated 1
DDB1 and CUL4 associated factor 7
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Intermembrane Space
Cytosol
Perinuclear Region Of Cytoplasm
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Nuclear Matrix
Nuclear Body
Protein-containing Complex
Cul4-RING E3 Ubiquitin Ligase Complex
Molecular Function
DNA Binding
Protein Binding
NAD(P)H Oxidase H2O2-forming Activity
Oxidoreductase Activity, Acting On NAD(P)H
Protein Dimerization Activity
FAD Binding
Protein Binding
Protein-macromolecule Adaptor Activity
Biological Process
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Chromosome Condensation
Mitochondrial Respiratory Chain Complex Assembly
Positive Regulation Of Apoptotic Process
Protein Import Into Mitochondrial Intermembrane Space
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Multicellular Organism Development
Protein Ubiquitination
Post-translational Protein Modification
Pathways
Association of TriC/CCT with target proteins during biosynthesis
Neddylation
Drugs
Flavin adenine dinucleotide
MCC
Diseases
Combined oxidative phosphorylation deficiency (COXPD)
GWAS
Bipolar disorder (
31043756
)
Interacting Genes
11 interacting genes:
CASP3
EIF3G
HSPA1A
HSPA1B
MLH1
NOA1
SETDB1
STC2
TSC22D4
WWC1
XIAP
7 interacting genes:
APP
ATP13A2
BMPR1B
DYRK1B
LIG1
PWP2
YWHAG
Entrez ID
9131
10238
HPRD ID
02161
09340
Ensembl ID
ENSG00000156709
ENSG00000136485
Uniprot IDs
E9PMA0
O95831
P61962
PDB IDs
1M6I
4BUR
4BV6
4FDC
4LII
5FMH
5FS6
5FS7
5FS8
5FS9
5KVH
5KVI
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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