SLC25A46 and FUNDC1

Data Source:
BioGRID (two hybrid)

		SLC25A46	FUNDC1
Description		solute carrier family 25 member 46	FUN14 domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Integral Component Of Membrane	Mitochondrial Outer Membrane Integral Component Of Mitochondrial Outer Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitochondrial Membrane Fission	Autophagy Of Mitochondrion Response To Hypoxia Response To Organonitrogen Compound Macroautophagy
Pathways			Receptor Mediated Mitophagy
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic sensitization ( 23817571) Asthma ( 31959851 30929738 27182965 31619474 29273806) Asthma (adult onset) ( 31036433 30929738) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma and hay fever ( 24388013) Asthma onset (childhood vs adult) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Cardiac structure and function ( 19584346) Medication use (adrenergics, inhalants) ( 31015401) Medication use (antihistamines for systemic use) ( 31015401) Thrombin-activatable fibrinolysis inhibitor levels ( 29378355) Uterine fibroid size (maximum volume) ( 30196971)	Facial morphology (factor 22) ( 28441456) Personality dimensions ( 18957941)
Interacting Genes		16 interacting genes: AQP6 FHL3 FUNDC1 HSD17B11 HSD17B13 LEPROTL1 MFSD14B ODF4 REEP2 REEP4 SLC10A1 SLC10A6 SLC66A2 SLC7A8 SPCS1 VMA21	15 interacting genes: CTBP1 CTBP2 EHHADH GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MARCHF5 MTERF3 SENP2 SH3GLB1 SLC25A46 SNX1 TUFM YES1
Entrez ID		91137	139341
HPRD ID		14283	06658
Ensembl ID		ENSG00000164209	ENSG00000069509
Uniprot IDs		B4DY98 Q96AG3	Q8IVP5
PDB IDs			2N9X 5GMV
Enriched GO Terms of Interacting Partners?
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