FUNDC1 and SH3GLB1

Data Source:
BioGRID (two hybrid)

		FUNDC1	SH3GLB1
Description		FUN14 domain containing 1	SH3 domain containing GRB2 like, endophilin B1
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GO Annotations	Cellular Component	Mitochondrial Outer Membrane Integral Component Of Mitochondrial Outer Membrane	Golgi Membrane Autophagosome Membrane Cytoplasm Mitochondrial Outer Membrane Cytosol Midbody Cytoplasmic Vesicle Protein-containing Complex
	Molecular Function	Protein Binding	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Autophagy Of Mitochondrion Response To Hypoxia Response To Organonitrogen Compound Macroautophagy	Autophagy Apoptotic Process Positive Regulation Of Autophagy Regulation Of Macroautophagy Positive Regulation Of Protein-containing Complex Assembly Regulation Of Protein Stability Regulation Of Cytokinesis Receptor Catabolic Process Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Autophagic Cell Death Membrane Fission Positive Regulation Of Membrane Tubulation Protein Localization To Vacuolar Membrane Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Autophagosome Assembly
Pathways		Receptor Mediated Mitophagy
Drugs
Diseases
GWAS		Facial morphology (factor 22) ( 28441456) Personality dimensions ( 18957941)
Interacting Genes		15 interacting genes: CTBP1 CTBP2 EHHADH GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MARCHF5 MTERF3 SENP2 SH3GLB1 SLC25A46 SNX1 TUFM YES1	52 interacting genes: ABHD5 ADAM15 ADAM9 AGTRAP AMPH APP ARFIP2 ARHGAP17 BAX BIN1 C1D CACFD1 CDKN2D CMTM5 COQ8A DESI2 DNM2 EXOSC5 F8A1 FAM114A2 FN1 FUNDC1 GADD45A GADD45G GSTP1 HTATIP2 HTT IRGM ITGB1BP2 MAL2 MTA1 PSMA1 RABAC1 RABGGTB RHEX RIC8A SH3GLB2 SH3KBP1 SIN3A SMIM5 SNX1 SNX4 SYNGR3 SYNJ1 SYP TAX1BP1 TFIP11 TPD52 TPD52L2 TTN UBL7 ZNF576
Entrez ID		139341	51100
HPRD ID		06658	15333
Ensembl ID		ENSG00000069509	ENSG00000097033
Uniprot IDs		Q8IVP5	A0A087WW40 A0A140VJU5 Q9Y371
PDB IDs		2N9X 5GMV	6UP6 6UPN
Enriched GO Terms of Interacting Partners?
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