UNC119 and TRDMT1

Data Source:
HPRD (two hybrid)

		UNC119	TRDMT1
Description		unc-119 lipid binding chaperone	tRNA aspartic acid methyltransferase 1
Image
GO Annotations	Cellular Component	Spindle Pole Centrosome Cytosol Intercellular Bridge Synapse Spindle Midzone	Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Lipid Binding	RNA Binding TRNA Methyltransferase Activity TRNA (cytosine-5-)-methyltransferase Activity
	Biological Process	Mitotic Cytokinesis Endocytosis Chemical Synaptic Transmission Nervous System Development Visual Perception Phototransduction Lipoprotein Transport Positive Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis	Response To Amphetamine TRNA Modification TRNA Methylation TRNA Stabilization
Pathways			tRNA modification in the nucleus and cytosol
Drugs			Pentamidine S-adenosyl-L-homocysteine Glycerin
Diseases
GWAS			Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Telomere length ( 24478790)
Interacting Genes		103 interacting genes: AAGAB ALDH2 AMOT ANKRD24 ANXA1 ANXA3 ANXA7 ARL15 ARL2 ARL3 ARL4D ASH2L BCR BRIX1 BTBD2 C16orf74 CBX8 CCL18 CD247 CD3E CD4 CDC42 CDKN1A CDKN2C CETN3 CKMT2 CKS2 COX17 CYB561D2 EIF2S2 ERH FKBPL FXYD6 FYN GIPC2 GSTM4 HCK HLA-DQA1 HMGB1 HSPB3 HSPE1 ID2 IL5RA ITSN1 KDM1A KRTAP1-3 KRTAP9-3 KRTAP9-8 LAMA4 LCK LIG4 LRIF1 LUC7L2 LYN MAP3K20 MAPK10 MAPK8IP2 MPHOSPH6 MRPS12 ORAI2 PAFAH1B3 PAPSS1 PCDHA4 PFN1 PHF10 PIN1 PLPP2 PPA1 PPP3CA PPP3CC PSMD11 PSMD2 PTPRS QTRT1 RAP1B RASSF6 RBPMS2 RCAN3 RCC1 RFC5 RGL2 RPA2 RPS6KA5 RUFY3 S100A4 S100A8 SAT1 SEPHS1 SERPINB9 SMN1 SULT1E1 TK1 TMEM200A TP53BP2 TP53I3 TP53INP1 TRDMT1 TSC22D1 UBE2B UBE2I UBQLN4 ZFP64 ZNF24	14 interacting genes: APP COPS6 DDX24 EEF1A1 GBE1 LRIF1 NFRKB RBM48 SETDB1 SNRPD3 STX1A TBC1D2B UNC119 UTP14A
Entrez ID		9094	1787
HPRD ID		04927	16001
Ensembl ID		ENSG00000109103	ENSG00000107614
Uniprot IDs		K7EN86 Q13432	A0A0U1U562 B4DQZ2 O14717 Q6ICS7 Q7Z3E4
PDB IDs		3GQQ 3RBQ 4GOJ 4GOK 5L7K 6H6A	1G55
Enriched GO Terms of Interacting Partners?
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