DNAJA3 and TCF19

Data Source:
BioGRID (two hybrid)

		DNAJA3	TCF19
Description		DnaJ heat shock protein family (Hsp40) member A3	transcription factor 19
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Cytosol Actin Filament Extrinsic Component Of Plasma Membrane Neuromuscular Junction Intracellular Membrane-bounded Organelle Postsynaptic Membrane	Nucleus
	Molecular Function	Protein Binding ATP Binding Hsp70 Protein Binding GTPase Regulator Activity Metal Ion Binding Unfolded Protein Binding	DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Mitochondrial DNA Replication Protein Folding Activation-induced Cell Death Of T Cells Mitochondrion Organization Small GTPase Mediated Signal Transduction Cell Aging Negative Regulation Of Cell Population Proliferation Response To Heat T Cell Differentiation In Thymus Positive Regulation Of T Cell Proliferation Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Catalytic Activity Skeletal Muscle Acetylcholine-gated Channel Clustering	Regulation Of Transcription, DNA-templated Regulation Of Gene Expression
Pathways
Drugs
Diseases
GWAS		Erectile dysfunction ( 30583798) Immature fraction of reticulocytes ( 32888494) Schizophrenia ( 28991256) Triglyceride levels ( 32203549) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Chronic hepatitis B infection ( 25802187 23760081) Idiopathic membranous nephropathy ( 21323541) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Marginal zone lymphoma ( 25569183) Multiple myeloma ( 23955597) Night sleep phenotypes ( 27126917) Refractive error ( 32231278) Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) ( 21912425) Type 2 diabetes ( 24509480 30718926) Ulcerative colitis ( 28067908) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes		44 interacting genes: ATXN1 BRCA1 C2CD6 CARM1 CIDEB COIL CYSRT1 FAM131C FAM214B FBXO7 FOSL2 FRMD6 GCC1 GFI1B GRB2 HSPA1A HSPA8 IFNGR2 INPP5J JAK2 KDM1A KRAS LAMTOR5 MCPH1 MET MYO15B NFKBIA NFKBIB NOC4L NTRK1 OSGIN1 PRMT6 PTEN RAD51 RASA1 RELA RNF34 SMAD9 SMARCB1 STK16 TCF19 USP7 VHL ZBTB22	19 interacting genes: APP BLZF1 CEP76 DNAJA3 GOLGA2 H3-4 H4-16 HOXA1 HSF2BP LZTR1 NFKBID NOXA1 PDLIM7 PFDN5 PRKAB2 RHOH TRIB3 UBE3A ZNF474
Entrez ID		9093	6941
HPRD ID		09758	15986
Ensembl ID		ENSG00000103423	ENSG00000137310
Uniprot IDs		B3KM81 Q53G26 Q59E88 Q96EY1	A0A1U9X8M7 Q9Y242
PDB IDs		2CTT 2DN9 6IWS
Enriched GO Terms of Interacting Partners?
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