CD1A and DGAT1

Data Source:
BioGRID (two hybrid)

		CD1A	DGAT1
Description		CD1a molecule	diacylglycerol O-acyltransferase 1
Image
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Endosome Membrane Membrane Raft	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Specific Granule Membrane
	Molecular Function	Protein Binding Endogenous Lipid Antigen Binding Exogenous Lipid Antigen Binding Lipopeptide Binding	2-acylglycerol O-acyltransferase Activity Diacylglycerol O-acyltransferase Activity Protein Binding O-acyltransferase Activity Transferase Activity, Transferring Acyl Groups Identical Protein Binding Retinol O-fatty-acyltransferase Activity
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Adaptive Immune Response Immune Response Antigen Processing And Presentation, Endogenous Lipid Antigen Via MHC Class Ib Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Regulation Of Immune Response	Monoacylglycerol Biosynthetic Process Triglyceride Metabolic Process Triglyceride Biosynthetic Process Lipid Storage Very-low-density Lipoprotein Particle Assembly Long-chain Fatty-acyl-CoA Metabolic Process Acylglycerol Acyl-chain Remodeling Retinol Metabolic Process Neutrophil Degranulation Diacylglycerol Metabolic Process Fatty Acid Homeostasis
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Acyl chain remodeling of DAG and TAG Neutrophil degranulation Triglyceride biosynthesis
Drugs		Antithymocyte immunoglobulin (rabbit)
Diseases
GWAS		Change in neurofilament light levels ( 31295725) Dental caries (decayed and filled deciduous teeth) ( 31533690)	Dupuytren's disease ( 28886342)
Interacting Genes		4 interacting genes: B2M DGAT1 KCTD5 UBTD1	3 interacting genes: CCR9 CD1A GABRA4
Entrez ID		909	8694
HPRD ID		01776	05360
Ensembl ID		ENSG00000158477	ENSG00000185000
Uniprot IDs		P06126	O75907
PDB IDs		1ONQ 1XZ0 4X6C 4X6D 4X6E 4X6F 5J1A 6NUX	6VP0 6VYI 6VZ1
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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