ZNF835 and POLR1C

Data Source:
BioGRID (two hybrid)

		ZNF835	POLR1C
Description		zinc finger protein 835	RNA polymerase I and III subunit C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleoplasm RNA Polymerase III Complex RNA Polymerase I Complex Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	RNA Polymerase I Activity RNA Polymerase III Activity DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Protein Dimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Transcription By RNA Polymerase I Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription By RNA Polymerase III Positive Regulation Of Type I Interferon Production Positive Regulation Of Gene Expression, Epigenetic
Pathways			Cytosolic sensors of pathogen-associated DNA NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase III Chain Elongation RNA Polymerase I Transcription Termination RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases			Treacher Collins syndrome
GWAS		Western dietary pattern ( 28644415)	GLP-1 levels in response to oral glucose tolerance test (fasting) ( 29093273) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		67 interacting genes: BEGAIN BYSL CABP5 CCDC130 CCDC136 CCDC57 CCDC6 CCNDBP1 CDR2L CEP70 CIB3 CLK3 CYSRT1 DEUP1 FSD2 GOLGA2 GOLGA6L9 GOPC GRIPAP1 GUCD1 HAP1 HOOK2 HOXB1 HSF2BP IKBKG IL16 KIFC3 KRT31 KRTAP12-3 KRTAP4-5 LDOC1 MAGOHB MKRN3 MYF5 OSBPL3 POLR1C PRDM14 RINT1 RNF187 RUNDC3A SHCBP1L SHFL SPATA2 STAMBPL1 STX1A TEX12 TLE5 TRAF4 TRIM23 TRIM41 TSPYL2 TULP3 TXK U2AF2 ZNF121 ZNF202 ZNF343 ZNF497 ZNF524 ZNF526 ZNF552 ZNF572 ZNF629 ZNF71 ZNF768 ZNF792 ZNF837	119 interacting genes: ADAMTSL4 ARHGEF5 ATRIP AVPI1 BHLHB9 BIN3 BIRC7 BLZF1 C1orf105 C21orf58 C4orf45 CBX8 CBY2 CCDC33 CCNK CCT3 CGGBP1 CLU CORO1A CORO1B CRACR2A EFHC2 EP400 FH FMR1 FOXR2 GAS8 GMPPB GOLGA6A GOLGA6L9 GRPEL1 GSTO2 HDX HNRNPH1 HOXB9 HOXD12 IHO1 IKZF3 INCA1 KCTD1 KCTD13 KLF15 KRT19 KRT75 KRT76 KRTAP12-2 KRTAP3-1 LNX2 LRIF1 LZTS1 LZTS2 MBIP MEI4 MEOX2 MKRN3 MORN3 MRPS23 MYD88 MYO5B NDUFB10 NEDD4 NFKBIB NIF3L1 NME1 NME4 PIH1D2 POLDIP3 POLR1D POLR1E POLR1G POLR2G POLR2J POLR2J3 PPP2R3C PSMA1 RBM48 RIMBP3 RIMBP3C RSPH14 RUSC1 SAXO1 SMN1 SMN2 SORBS3 SPATC1L SPRY1 STMN3 TASOR2 TAX1BP1 TCF4 TEX43 TFIP11 TLE5 TMEM121 TNFAIP1 TNNI1 TRAIP TRIM14 TRIM27 TRIOBP TSC22D4 UNKL USP54 VIM WASHC1 WRN XPA YPEL3 ZBED1 ZBTB42 ZC2HC1C ZFP57 ZIM2 ZNF547 ZNF554 ZNF655 ZNF688 ZNF835 ZRANB1
Entrez ID		90485	9533
HPRD ID		12521	09661
Ensembl ID		ENSG00000127903	ENSG00000171453
Uniprot IDs		Q9Y2P0	O15160
PDB IDs
Enriched GO Terms of Interacting Partners?
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