TSPAN18 and OLFM4

Data Source:
BioGRID (two hybrid)

		TSPAN18	OLFM4
Description		tetraspanin 18	olfactomedin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane	Extracellular Region Extracellular Space Nucleoplasm Mitochondrion Cytosol Plasma Membrane Secretory Granule Protein-containing Complex Specific Granule Lumen Specific Granule Azurophil Granule Intercellular Bridge Perinuclear Region Of Cytoplasm Extracellular Exosome Tertiary Granule Lumen
	Molecular Function		Catalytic Activity Structural Molecule Activity Protein Binding Cadherin Binding
	Biological Process		Cell Adhesion Regulation Of Necrotic Cell Death Regulation Of Apoptotic Process Neutrophil Degranulation Regulation Of Phagocytosis Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Neutrophil Extravasation
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Intraocular pressure ( 29785010) Obstructive sleep apnea trait (average respiratory event duration) ( 26977737) Schizophrenia ( 22037552) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355)	Adult body size ( 32376654) Adventurousness ( 30643258) Amyotrophic lateral sclerosis (sporadic) ( 24529757) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 29381148 26961502 24861553 25673413 28448500 25953783) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body size at age 10 ( 32376654) Cerebrospinal P-tau181p levels ( 28247064) Childhood body mass index ( 26604143) Depression ( 29700475) Hip circumference ( 25673412) Immune response to anthrax vaccine ( 22658931) Intelligence (MTAG) ( 29326435) Major depressive disorder ( 27479909) Obesity ( 23563607 22484627) Obesity-related traits ( 23251661) Waist circumference ( 25673412)
Interacting Genes		9 interacting genes: CD151 CXCL9 GIMAP5 GRM2 IL1RL1 OLFM4 TMCO5A TMEM120A TMEM218	34 interacting genes: APP AQP2 AQP3 BSCL2 C3 CLDN7 CLEC17A CLEC7A CLSTN3 CLTRN CREB3L1 EREG FAM209A FNDC9 IL11RA ITM2C KASH5 KIR2DL3 KIR3DL3 LDLRAD1 LEUTX LHFPL2 PVR PVRIG QPCTL SLC18A1 SLC22A23 SUSD3 SYNE4 TFR2 TMEM130 TNFSF11 TNFSF14 TSPAN18
Entrez ID		90139	10562
HPRD ID		17435	06580
Ensembl ID		ENSG00000157570	ENSG00000102837
Uniprot IDs		Q96SJ8	A0A024QZ95 Q6UX06
PDB IDs
Enriched GO Terms of Interacting Partners?
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