OLFM4 and CLTRN

Data Source:
BioGRID (two hybrid)

		OLFM4	CLTRN
Description		olfactomedin 4	collectrin, amino acid transport regulator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Mitochondrion Cytosol Plasma Membrane Secretory Granule Protein-containing Complex Specific Granule Lumen Specific Granule Azurophil Granule Intercellular Bridge Perinuclear Region Of Cytoplasm Extracellular Exosome Tertiary Granule Lumen	Cytoplasm Plasma Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Catalytic Activity Structural Molecule Activity Protein Binding Cadherin Binding	Protein Binding Protein Homodimerization Activity
	Biological Process	Cell Adhesion Regulation Of Necrotic Cell Death Regulation Of Apoptotic Process Neutrophil Degranulation Regulation Of Phagocytosis Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Neutrophil Extravasation	Regulation Of Transmembrane Transporter Activity Positive Regulation Of SNARE Complex Assembly Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Amino Acid Transport Positive Regulation Of L-proline Import Across Plasma Membrane
Pathways		Neutrophil degranulation	Insulin processing
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Amyotrophic lateral sclerosis (sporadic) ( 24529757) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 29381148 26961502 24861553 25673413 28448500 25953783) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body size at age 10 ( 32376654) Cerebrospinal P-tau181p levels ( 28247064) Childhood body mass index ( 26604143) Depression ( 29700475) Hip circumference ( 25673412) Immune response to anthrax vaccine ( 22658931) Intelligence (MTAG) ( 29326435) Major depressive disorder ( 27479909) Obesity ( 23563607 22484627) Obesity-related traits ( 23251661) Waist circumference ( 25673412)
Interacting Genes		34 interacting genes: APP AQP2 AQP3 BSCL2 C3 CLDN7 CLEC17A CLEC7A CLSTN3 CLTRN CREB3L1 EREG FAM209A FNDC9 IL11RA ITM2C KASH5 KIR2DL3 KIR3DL3 LDLRAD1 LEUTX LHFPL2 PVR PVRIG QPCTL SLC18A1 SLC22A23 SUSD3 SYNE4 TFR2 TMEM130 TNFSF11 TNFSF14 TSPAN18	4 interacting genes: OLFM4 RBM18 SMCO4 UBE2J1
Entrez ID		10562	57393
HPRD ID		06580	06668
Ensembl ID		ENSG00000102837	ENSG00000147003
Uniprot IDs		A0A024QZ95 Q6UX06	A0A3B3ITM8 Q9HBJ8
PDB IDs
Enriched GO Terms of Interacting Partners?
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