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PPOX

Description protoporphyrinogen oxidase
Image
GO Annotations Cellular Component
  • Mitochondrial Intermembrane Space
  • Intrinsic Component Of Mitochondrial Inner Membrane
  • Integral Component Of Mitochondrial Inner Membrane
  • Mitochondrial Membrane
Molecular Function
  • Oxygen-dependent Protoporphyrinogen Oxidase Activity
  • Oxidoreductase Activity
  • Flavin Adenine Dinucleotide Binding
Biological Process
  • Porphyrin-containing Compound Biosynthetic Process
  • Protoporphyrinogen IX Biosynthetic Process
  • Heme Biosynthetic Process
  • Response To Drug
Pathways
  • Heme biosynthesis
Drugs
Diseases
  • Hepatic porphyria, including: Porphyria Cutanea Tarda (PCT); VHepatoerythropoietic porphyria; Acute Intermittent Porphyria (AIP); Variegate porphyria (VP); ALA-dehydratase deficiency porphyria (ALADP); Hereditary Coproporphyria (HCP)
GWAS
Interacting Genes 4 interacting genes: COPS5 HAP1 HNRNPD IMMT
Entrez ID 5498
HPRD ID 02953
Ensembl ID ENSG00000143224
Uniprot IDs P50336
PDB IDs 3NKS 4IVM 4IVO
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025