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WASL and TRIP10
Data Source:
BioGRID
(biochemical, two hybrid, pull down)
WASL
TRIP10
Description
WASP like actin nucleation promoting factor
thyroid hormone receptor interactor 10
Image
GO Annotations
Cellular Component
Nucleus
Cytosol
Actin Filament
Plasma Membrane
Actin Cytoskeleton
Lamellipodium
Actin Cap
Endocytic Vesicle Membrane
Cytoplasmic Vesicle
Extracellular Exosome
Phagocytic Cup
Nucleoplasm
Cytoplasm
Lysosome
Golgi Apparatus
Cytosol
Cytoskeleton
Cell Cortex
Cell Projection
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Molecular Function
Actin Binding
Protein Binding
GTPase Regulator Activity
Protein Binding
Lipid Binding
Identical Protein Binding
Biological Process
Vesicle Budding From Membrane
Actin Polymerization Or Depolymerization
Response To Bacterium
Vesicle Organization
Actin Filament Polymerization
Actin Filament-based Movement
Vesicle Transport Along Actin Filament
Regulation Of Protein Localization
Cellular Protein-containing Complex Localization
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Positive Regulation Of Transcription By RNA Polymerase II
Ephrin Receptor Signaling Pathway
Regulation Of Nitric-oxide Synthase Activity
Cell Division
Positive Regulation Of Filopodium Assembly
Spindle Localization
Dendritic Spine Morphogenesis
Membrane Organization
Protein-containing Complex Assembly
Negative Regulation Of Membrane Tubulation
Positive Regulation Of Clathrin-dependent Endocytosis
Negative Regulation Of Lymphocyte Migration
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Endocytosis
Cell Communication
Signal Transduction
Actin Cytoskeleton Organization
Regulation Of Small GTPase Mediated Signal Transduction
Membrane Organization
Pathways
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
NOSTRIN mediated eNOS trafficking
Nephrin family interactions
EPHB-mediated forward signaling
EPHB-mediated forward signaling
DCC mediated attractive signaling
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
Clathrin-mediated endocytosis
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Rho GTPase cycle
Clathrin-mediated endocytosis
Drugs
Diseases
GWAS
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Platelet count (
22139419
27863252
)
Plateletcrit (
27863252
)
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Interacting Genes
63 interacting genes:
ABI2
ABL1
ACTG1
ACTR2
ACTR3
APBB1
APP
ARHGAP12
ARPC3
ARPC4
BIN1
CDC42
CORO7
CTTN
DNMBP
EGFR
EVL
FCHSD2
FNBP1
FNBP1L
GRB2
HP
HSP90AA1
HSP90AB1
IPO5
ITCH
ITGB1BP2
ITSN1
ITSN2
LCK
NCK1
NCK2
NCKIPSD
OSTF1
PACSIN1
PACSIN2
PACSIN3
PFN1
PRMT2
PRPF40A
PSTPIP1
PTK6
RHOJ
RHOQ
RNF8
RPL7AP66
SDCBP
SH3GL3
SH3RF1
SNX9
SORBS2
SRC
TNNT3
TRIP10
UBASH3A
UBASH3B
VASP
VIPR1
WIPF1
WIPF2
WIPF3
WWP1
ZNF395
41 interacting genes:
ABI1
ABL2
AKAP9
ARHGAP12
ARHGAP17
CDC42
CREBBP
CTNNB1
DNM2
DTX3
HOXC11
HTT
JRK
LYN
MEOX1
MEOX2
NKX2-5
PAX6
PDE6G
POT1
PRKACA
RHOJ
RHOQ
RIN1
RXRA
SF3A2
SH3BP1
SMARCE1
SMURF1
SRC
STAT3
TERF1
THAP1
THRB
TINF2
UTF1
WAS
WASF1
WASL
WBP11
ZBTB7B
Entrez ID
8976
9322
HPRD ID
05448
05142
Ensembl ID
ENSG00000106299
ENSG00000125733
Uniprot IDs
O00401
Q15642
W4VSQ9
PDB IDs
2FF3
2LNH
2VCP
4CC2
4CC7
2CT4
2EFK
2KE4
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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