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WASL and ITGB1BP2
Data Source:
BioGRID
(two hybrid)
WASL
ITGB1BP2
Description
WASP like actin nucleation promoting factor
integrin subunit beta 1 binding protein 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytosol
Actin Filament
Plasma Membrane
Actin Cytoskeleton
Lamellipodium
Actin Cap
Endocytic Vesicle Membrane
Cytoplasmic Vesicle
Extracellular Exosome
Z Disc
Molecular Function
Actin Binding
Protein Binding
GTPase Regulator Activity
Integrin Binding
Calcium Ion Binding
Protein Binding
Zinc Ion Binding
SH3 Domain Binding
Biological Process
Vesicle Budding From Membrane
Actin Polymerization Or Depolymerization
Response To Bacterium
Vesicle Organization
Actin Filament Polymerization
Actin Filament-based Movement
Vesicle Transport Along Actin Filament
Regulation Of Protein Localization
Cellular Protein-containing Complex Localization
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Positive Regulation Of Transcription By RNA Polymerase II
Ephrin Receptor Signaling Pathway
Regulation Of Nitric-oxide Synthase Activity
Cell Division
Positive Regulation Of Filopodium Assembly
Spindle Localization
Dendritic Spine Morphogenesis
Membrane Organization
Protein-containing Complex Assembly
Negative Regulation Of Membrane Tubulation
Positive Regulation Of Clathrin-dependent Endocytosis
Negative Regulation Of Lymphocyte Migration
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Signal Transduction
Muscle Organ Development
Pathways
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
NOSTRIN mediated eNOS trafficking
Nephrin family interactions
EPHB-mediated forward signaling
EPHB-mediated forward signaling
DCC mediated attractive signaling
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
Clathrin-mediated endocytosis
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Platelet count (
22139419
27863252
)
Plateletcrit (
27863252
)
Reticulocyte count (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Interacting Genes
63 interacting genes:
ABI2
ABL1
ACTG1
ACTR2
ACTR3
APBB1
APP
ARHGAP12
ARPC3
ARPC4
BIN1
CDC42
CORO7
CTTN
DNMBP
EGFR
EVL
FCHSD2
FNBP1
FNBP1L
GRB2
HP
HSP90AA1
HSP90AB1
IPO5
ITCH
ITGB1BP2
ITSN1
ITSN2
LCK
NCK1
NCK2
NCKIPSD
OSTF1
PACSIN1
PACSIN2
PACSIN3
PFN1
PRMT2
PRPF40A
PSTPIP1
PTK6
RHOJ
RHOQ
RNF8
RPL7AP66
SDCBP
SH3GL3
SH3RF1
SNX9
SORBS2
SRC
TNNT3
TRIP10
UBASH3A
UBASH3B
VASP
VIPR1
WIPF1
WIPF2
WIPF3
WWP1
ZNF395
14 interacting genes:
HSP90AA1
HSP90AB1
ITGB1
PPHLN1
PUM3
RARA
RARG
SGCA
SH3GLB1
STAG2
TKT
TTN
UGDH
WASL
Entrez ID
8976
26548
HPRD ID
05448
02271
Ensembl ID
ENSG00000106299
ENSG00000147166
Uniprot IDs
O00401
Q9UKP3
PDB IDs
2FF3
2LNH
2VCP
4CC2
4CC7
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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