MBD2 and MBD3L2

Data Source:
BioGRID (pull down)

		MBD2	MBD3L2
Description		methyl-CpG binding domain protein 2	methyl-CpG binding domain protein 3 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Chromatin Heterochromatin Nucleus Nucleoplasm Cytosol Protein-containing Complex
	Molecular Function	Satellite DNA Binding MRNA Binding Protein Binding Methyl-CpG Binding Protein Domain Specific Binding Nucleosomal DNA Binding SiRNA Binding C2H2 Zinc Finger Domain Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II RDNA Heterochromatin Assembly DNA Methylation-dependent Heterochromatin Assembly Heart Development Aging Response To Mechanical Stimulus Positive Regulation Of Wnt Signaling Pathway Response To Nutrient Levels Response To Estradiol Cellular Protein-containing Complex Assembly Positive Regulation Of Chromatin Binding Regulation Of Cell Population Proliferation Maternal Behavior ATP-dependent Chromatin Remodeling Regulation Of DNA Methylation Negative Regulation Of Transcription, DNA-templated Embryonic Organ Development Cellular Response To Organic Cyclic Compound
Pathways		NoRC negatively regulates rRNA expression RNA Polymerase I Promoter Opening
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Body size at age 10 ( 32376654) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Nickel levels ( 26025379) Periodontitis (Mean PAL) ( 24024966) Prostate cancer ( 29892016) Psoriasis ( 23143594)
Interacting Genes		16 interacting genes: CREBBP DHX9 GATAD2A GATAD2B GPN1 HDAC1 HDAC2 HINFP LAMTOR3 MBD3 MBD3L1 MBD3L2 PURB RBBP4 SIN3A TBP	20 interacting genes: CCDC136 CHD4 GOLGA6L9 GPRASP2 HDAC1 HDAC2 KRT27 KRT34 KRTAP6-3 MBD2 MBD3 MDFI MTA1 MTA2 POLD3 RBBP4 RBBP7 RUNDC3A SBK3 TRIML2
Entrez ID		8932	125997
HPRD ID		04647	12139
Ensembl ID		ENSG00000134046	ENSG00000230522
Uniprot IDs		A0A024R2B8 Q9UBB5	Q8NHZ7
PDB IDs		2L2L 6C1A 6C1T 6C1U 6C1V 6C2F 6CNP 6CNQ
Enriched GO Terms of Interacting Partners?
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