MBD4 and CDCA2

Data Source:
BioGRID (two hybrid)

		MBD4	CDCA2
Description		methyl-CpG binding domain 4, DNA glycosylase	cell division cycle associated 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Nucleoplasm Chromosome Cytosol
	Molecular Function	DNA Binding Satellite DNA Binding Endodeoxyribonuclease Activity Protein Binding Pyrimidine-specific Mismatch Base Pair DNA N-glycosylase Activity DNA N-glycosylase Activity
	Biological Process	DNA Repair Response To Estradiol Depyrimidination	Cell Cycle Chromosome Segregation Positive Regulation Of Protein Dephosphorylation Cell Division
Pathways		Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Displacement of DNA glycosylase by APEX1
Drugs
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	HDL cholesterol levels ( 32203549) Major depressive disorder ( 27479909) Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306) Systolic blood pressure x quantitative lifestyle risk score interaction (1df test) ( 32227373) Systolic blood pressure x quantitative lifestyle risk score interaction (2df test) ( 32227373) Triglyceride levels ( 32203549)
Interacting Genes		15 interacting genes: CDCA2 CSNK2B DNMT3B FADD FAS HDAC1 KDM1A MLH1 NAT2 SIN3A SUV39H1 TRIM27 TRIM55 TRIM63 UHRF1	2 interacting genes: CDK1 MBD4
Entrez ID		8930	157313
HPRD ID		04654	13014
Ensembl ID		ENSG00000129071	ENSG00000184661
Uniprot IDs		O95243	A8K8Z0 B7Z5Q5 E9PEI0 Q69YH5
PDB IDs		2MOE 3IHO 4DK9 4E9E 4E9F 4E9G 4E9H 4EA4 4EA5 4LG7 4OFA 4OFE 4OFH 5CHZ	5INB 5IOH 5SW9
Enriched GO Terms of Interacting Partners?
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