CDCA2 and MBD4

Data Source:
BioGRID (two hybrid)

		CDCA2	MBD4
Description		cell division cycle associated 2	methyl-CpG binding domain 4, DNA glycosylase
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GO Annotations	Cellular Component	Nucleoplasm Chromosome Cytosol	Nucleus Nucleoplasm Nuclear Speck
	Molecular Function		DNA Binding Satellite DNA Binding Endodeoxyribonuclease Activity Protein Binding Pyrimidine-specific Mismatch Base Pair DNA N-glycosylase Activity DNA N-glycosylase Activity
	Biological Process	Cell Cycle Chromosome Segregation Positive Regulation Of Protein Dephosphorylation Cell Division	DNA Repair Response To Estradiol Depyrimidination
Pathways			Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Displacement of DNA glycosylase by APEX1
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Major depressive disorder ( 27479909) Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306) Systolic blood pressure x quantitative lifestyle risk score interaction (1df test) ( 32227373) Systolic blood pressure x quantitative lifestyle risk score interaction (2df test) ( 32227373) Triglyceride levels ( 32203549)	Diisocyanate-induced asthma ( 25918132) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		2 interacting genes: CDK1 MBD4	15 interacting genes: CDCA2 CSNK2B DNMT3B FADD FAS HDAC1 KDM1A MLH1 NAT2 SIN3A SUV39H1 TRIM27 TRIM55 TRIM63 UHRF1
Entrez ID		157313	8930
HPRD ID		13014	04654
Ensembl ID		ENSG00000184661	ENSG00000129071
Uniprot IDs		A8K8Z0 B7Z5Q5 E9PEI0 Q69YH5	O95243
PDB IDs		5INB 5IOH 5SW9	2MOE 3IHO 4DK9 4E9E 4E9F 4E9G 4E9H 4EA4 4EA5 4LG7 4OFA 4OFE 4OFH 5CHZ
Enriched GO Terms of Interacting Partners?
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