GYG2 and GYS1

Data Source:
HPRD (in vitro, in vivo)

		GYG2	GYS1
Description		glycogenin 2	glycogen synthase 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Cytoplasm Cytosol Membrane Inclusion Body
	Molecular Function	Glycogenin Glucosyltransferase Activity Transferase Activity, Transferring Glycosyl Groups Metal Ion Binding UDP-alpha-D-glucose:glucosyl-glycogenin Alpha-D-glucosyltransferase Activity	Glycogen (starch) Synthase Activity Protein Binding Glucose Binding Protein Kinase Binding Glycogen Synthase Activity, Transferring Glucose-1-phosphate
	Biological Process	Glycogen Biosynthetic Process	Glycogen Biosynthetic Process Heart Development
Pathways		Glycogen synthesis Glycogen storage disease type 0 (liver GYS2) Glycogen storage disease type IV (GBE1) Glycogen breakdown (glycogenolysis)	Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage disease type XV (GYG1) Glycogen storage disease type 0 (muscle GYS1)
Drugs
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS
Interacting Genes		5 interacting genes: APP GYG1 GYS1 GYS2 IKBKG	43 interacting genes: AIMP2 APP BEND7 CCDC33 CDCA8 CLVS2 CRX CSNK2A1 EFHC2 FAM228A GSK3B GYG1 GYG2 HOXB6 HOXC8 IHO1 INCA1 KATNBL1 KLF1 KLF4 MAPKAPK5 MEOX1 NDUFB7 NHLRC1 PCYT1A PINX1 PLAGL2 PNMA5 PRKACA RBM48 SNIP1 SORBS3 SUMO2 TFAP2D TLE5 WASHC1 ZBTB33 ZNF212 ZNF326 ZNF474 ZNF552 ZNF620 ZNF774
Entrez ID		8908	2997
HPRD ID		02185	00721
Ensembl ID		ENSG00000056998	ENSG00000104812
Uniprot IDs		B3KUV6 O15488 Q1ZYL7	P13807
PDB IDs		4UEG
Enriched GO Terms of Interacting Partners?
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