BUD31 and ADCY7

Data Source:
BioGRID (two hybrid)

		BUD31	ADCY7
Description		BUD31 homolog	adenylate cyclase 7
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Nuclear Receptor Coactivator Activity Nuclear Hormone Receptor Binding	Adenylate Cyclase Activity ATP Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Androgen Receptor Activity	Regulation Of Adaptive Immune Response Renal Water Homeostasis CAMP Biosynthetic Process G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Activation Of Protein Kinase A Activity Maternal Process Involved In Female Pregnancy Cellular Response To Lithium Ion Cellular Response To Ethanol Cellular Response To Glucagon Stimulus Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Pathways		mRNA Splicing - Major Pathway	Glucagon signaling in metabolic regulation PKA activation PKA activation in glucagon signalling Adenylate cyclase activating pathway Adenylate cyclase inhibitory pathway Adenylate cyclase inhibitory pathway G alpha (s) signalling events G alpha (s) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events Vasopressin regulates renal water homeostasis via Aquaporins Hedgehog 'off' state ADORA2B mediated anti-inflammatory cytokines production ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis
Drugs
Diseases
GWAS		Facial emotion recognition (sad faces) ( 28608620) Serum metabolite levels ( 23093944)	Autoimmune thyroid disease ( 32581359) Crohn's disease ( 23128233) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Inflammatory bowel disease ( 28067908) Pediatric autoimmune diseases ( 26301688) Ulcerative colitis ( 28067908 28067910)
Interacting Genes		23 interacting genes: ADCY7 APP ATP13A1 BEND5 CCT3 CTNNBL1 ERGIC3 HLA-A HOXA1 HTR5A KRTAP10-3 KRTAP10-7 MARCHF6 MEOX2 MMP24 NPC1 PANX1 PICK1 RELB RNF208 SCAF1 TMEM94 TSPAN7	4 interacting genes: BUD31 PLSCR1 PRKCD XRCC6
Entrez ID		8896	113
HPRD ID		10351	02663
Ensembl ID		ENSG00000106245	ENSG00000121281
Uniprot IDs		P41223	B3KSJ0 F5H4D1 P51828 Q86YI0
PDB IDs		4OED 4OH6 4OKB 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM
Enriched GO Terms of Interacting Partners?
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