ADCY7 and BUD31

Data Source:
BioGRID (two hybrid)

		ADCY7	BUD31
Description		adenylate cyclase 7	BUD31 homolog
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Chromatin Nucleus Nucleoplasm Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome
	Molecular Function	Adenylate Cyclase Activity ATP Binding Metal Ion Binding	Protein Binding Nuclear Receptor Coactivator Activity Nuclear Hormone Receptor Binding
	Biological Process	Regulation Of Adaptive Immune Response Renal Water Homeostasis CAMP Biosynthetic Process G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Activation Of Protein Kinase A Activity Maternal Process Involved In Female Pregnancy Cellular Response To Lithium Ion Cellular Response To Ethanol Cellular Response To Glucagon Stimulus Negative Regulation Of Cytokine Production Involved In Inflammatory Response	MRNA Splicing, Via Spliceosome Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Androgen Receptor Activity
Pathways		Glucagon signaling in metabolic regulation PKA activation PKA activation in glucagon signalling Adenylate cyclase activating pathway Adenylate cyclase inhibitory pathway Adenylate cyclase inhibitory pathway G alpha (s) signalling events G alpha (s) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events Vasopressin regulates renal water homeostasis via Aquaporins Hedgehog 'off' state ADORA2B mediated anti-inflammatory cytokines production ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Autoimmune thyroid disease ( 32581359) Crohn's disease ( 23128233) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Inflammatory bowel disease ( 28067908) Pediatric autoimmune diseases ( 26301688) Ulcerative colitis ( 28067908 28067910)	Facial emotion recognition (sad faces) ( 28608620) Serum metabolite levels ( 23093944)
Interacting Genes		4 interacting genes: BUD31 PLSCR1 PRKCD XRCC6	23 interacting genes: ADCY7 APP ATP13A1 BEND5 CCT3 CTNNBL1 ERGIC3 HLA-A HOXA1 HTR5A KRTAP10-3 KRTAP10-7 MARCHF6 MEOX2 MMP24 NPC1 PANX1 PICK1 RELB RNF208 SCAF1 TMEM94 TSPAN7
Entrez ID		113	8896
HPRD ID		02663	10351
Ensembl ID		ENSG00000121281	ENSG00000106245
Uniprot IDs		B3KSJ0 F5H4D1 P51828 Q86YI0	P41223
PDB IDs			4OED 4OH6 4OKB 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM
Enriched GO Terms of Interacting Partners?
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