EIF2B2 and EIF2B4

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)
HPRD (in vivo, in vitro)

		EIF2B2	EIF2B4
Description		eukaryotic translation initiation factor 2B subunit beta	eukaryotic translation initiation factor 2B subunit delta
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex
	Molecular Function	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding ATP Binding GTP Binding	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Initiation Factor Binding
	Biological Process	Ovarian Follicle Development Translational Initiation Regulation Of Translational Initiation Central Nervous System Development Response To Heat Response To Glucose Oligodendrocyte Development Myelination Response To Peptide Hormone Regulation Of Catalytic Activity T Cell Receptor Signaling Pathway	Ovarian Follicle Development Translational Initiation Regulation Of Translation Response To Heat Response To Glucose Oligodendrocyte Development Myelination Response To Peptide Hormone Regulation Of Catalytic Activity T Cell Receptor Signaling Pathway
Pathways		Recycling of eIF2:GDP	Recycling of eIF2:GDP
Drugs
Diseases		Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)	Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
GWAS		Coronary artery disease ( 33020668) Mood instability ( 29187730) Youthful appearance (self-reported) ( 32339537)	Non-oily fish consumption ( 32066663)
Interacting Genes		12 interacting genes: APP C9orf72 CCT3 CSNK2A2 EIF2B1 EIF2B4 EIF2B5 EIF2S1 MRFAP1L1 NCK1 PCGF6 TET2	3 interacting genes: EIF2B2 EIF2S1 EIF2S2
Entrez ID		8892	8890
HPRD ID		05923	09459
Ensembl ID		ENSG00000119718	ENSG00000115211
Uniprot IDs		P49770 Q53XC2	B4DUP5 E7ERK9 F8W8L6 Q71US4 Q9HBP7 Q9UI10
PDB IDs		6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z	6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z
Enriched GO Terms of Interacting Partners?
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