IER3 and SLC13A4

Data Source:
BioGRID (two hybrid)

		IER3	SLC13A4
Description		immediate early response 3	solute carrier family 13 member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Protein Binding Sodium:sulfate Symporter Activity
	Biological Process	Apoptotic Process Anatomical Structure Morphogenesis Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Apoptotic Process Regulation Of Response To DNA Damage Stimulus	Sodium Ion Transport Sulfate Transport Anion Transmembrane Transport Sulfate Transmembrane Transport
Pathways		PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Sodium-coupled sulphate, di- and tri-carboxylate transporters
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23455636) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Chronic obstructive pulmonary disease ( 30804561) Decreased fine motor function in Charcot-Marie-Tooth disease 1A (eating with utensils) ( 30958311) Rosacea symptom severity ( 29771307) Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome) ( 26651848) Sleep duration ( 25469926) Small cell lung carcinoma ( 28604730) Type 1 diabetes and autoimmune thyroid diseases ( 25936594) Ulcerative colitis ( 20848476)	Alcoholic chronic pancreatitis ( 28754779) Diverticular disease ( 30177863)
Interacting Genes		17 interacting genes: APP AQP2 CD79A CISD2 FHL2 FKBP7 GLP1R MAPK1 MAPK3 MDM2 PPP2R5B PPP2R5C PRNP SGTA SLC13A4 TMBIM6 TMX2	26 interacting genes: ACKR2 CBLIF CD79A CDS1 CERS4 DEFB108B DERL3 EFNA5 EOGT ERMP1 FCER1G GJA5 GPR152 GPR61 IER3 IGFBP5 MS4A13 OPRD1 OTOP3 SLC35A4 SLC35E4 SLC38A1 SLC41A1 TMEM147 TMEM60 TRARG1
Entrez ID		8870	26266
HPRD ID		04295	10372
Ensembl ID		ENSG00000137331	ENSG00000164707
Uniprot IDs		A0A1U9X7X2 P46695	Q59HF0 Q9UKG4
PDB IDs
Enriched GO Terms of Interacting Partners?
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