ASAP2 and REPS2

		ASAP2	REPS2
Description		ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	RALBP1 associated Eps domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Golgi Cisterna Membrane	Cytoplasm Cytosol Plasma Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding	Calcium Ion Binding Protein Binding
	Biological Process	Positive Regulation Of GTPase Activity	Endocytosis Epidermal Growth Factor Receptor Signaling Pathway Endosomal Transport Membrane Organization Protein-containing Complex Assembly
Pathways			Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Chronic obstructive pulmonary disease ( 30804561) Pulse pressure ( 27841878 30578418) Urate levels ( 31578528)
Interacting Genes		14 interacting genes: APC ARF1 ARF5 ARF6 BIN1 GRB2 ITSN1 PACSIN3 PTK2B PXN RAN REPS2 SH3KBP1 THSD7A	13 interacting genes: AR ASAP1 ASAP2 CDK1 CDK5RAP2 EPN1 EPS15 GRB2 PXN RALB RALBP1 RELA REPS1
Entrez ID		8853	9185
HPRD ID		04820	02262
Ensembl ID		ENSG00000151693	ENSG00000169891
Uniprot IDs		O43150	Q8NFH8
PDB IDs			1IQ3
Enriched GO Terms of Interacting Partners?
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