SAP30 and CIR1

Data Source:
HPRD (two hybrid)

		SAP30	CIR1
Description		Sin3A associated protein 30	corepressor interacting with RBPJ, CIR1
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GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleoplasm	Nucleus Cytoplasm Centrosome Nuclear Speck Protein-containing Complex
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding	Transcription Corepressor Activity Protein Binding Protein Kinase Binding Histone Deacetylase Binding Protein-containing Complex Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Skeletal Muscle Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development MRNA Processing RNA Splicing Negative Regulation Of Transcription, DNA-templated
Pathways		HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS
Drugs
Diseases
GWAS			Accelerometer-based physical activity measurement (fraction of time with accelerations >425 milli-gravities) ( 29899525) Adult body size ( 32376654) Chronotype ( 30696823) Hand grip strength ( 29691431) Triglyceride levels ( 32203549)
Interacting Genes		26 interacting genes: BRMS1 BRMS1L CIR1 CYTOR H2AC16 H2BC21 H3-4 H4-16 HBP1 HDAC1 HDAC2 HTT ID3 ING1 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A YY1 ZNF395	14 interacting genes: CCDC33 CEP76 DPPA4 HDAC2 MB21D2 NCOR2 NEK6 RBPJ RP9 SAP30 SNW1 SRSF2 TCEA1 U2AF1
Entrez ID		8819	9541
HPRD ID		04540	05568
Ensembl ID		ENSG00000164105	ENSG00000138433
Uniprot IDs		O75446	Q86X95
PDB IDs		2KDP	6ZYM
Enriched GO Terms of Interacting Partners?
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