RGS9 and GUCY2D

Data Source:
HPRD (in vivo)

		RGS9	GUCY2D
Description		regulator of G protein signaling 9	guanylate cyclase 2D, retinal
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Postsynaptic Density Membrane Glutamatergic Synapse	Photoreceptor Outer Segment Nuclear Outer Membrane Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Photoreceptor Outer Segment Membrane Photoreceptor Disc Membrane
	Molecular Function	GTPase Activity GTPase Activator Activity	Peptide Receptor Activity Guanylate Cyclase Activity Protein Kinase Activity Protein Binding ATP Binding GTP Binding Signaling Receptor Activity Protein Homodimerization Activity
	Biological Process	Response To Amphetamine Protein Folding G Protein-coupled Receptor Signaling Pathway Dopamine Receptor Signaling Pathway Nervous System Development Visual Perception Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Response To Estradiol Intracellular Signal Transduction Positive Regulation Of GTPase Activity Positive Regulation Of NMDA Glutamate Receptor Activity Regulation Of Calcium Ion Export Across Plasma Membrane	CGMP Biosynthetic Process Protein Phosphorylation Signal Transduction Receptor Guanylyl Cyclase Signaling Pathway Visual Perception Regulation Of Rhodopsin Mediated Signaling Pathway Intracellular Signal Transduction
Pathways		G alpha (i) signalling events G alpha (i) signalling events Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	Inactivation, recovery and regulation of the phototransduction cascade
Drugs
Diseases		Bradyopsia	Leber congenital amaurosis (LCR) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS		Adverse response to antithyroid drugs in Graves disease ( 30067105) Heel bone mineral density ( 30598549 28869591)	Refractive error ( 32231278)
Interacting Genes		5 interacting genes: ADRB2 GNAT1 GNB5 GUCY2D RGS9BP	5 interacting genes: GUCA1A GUCA1B GUCA2B RGS9 S100B
Entrez ID		8787	3000
HPRD ID		04962	02550
Ensembl ID		ENSG00000108370	ENSG00000132518
Uniprot IDs		A8K1G1 O75916	Q02846
PDB IDs			1AWL
Enriched GO Terms of Interacting Partners?
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