TNFRSF18 and LGALS8

Data Source:
BioGRID (affinity chromatography technology)

		TNFRSF18	LGALS8
Description		TNF receptor superfamily member 18	galectin 8
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Extracellular Space Cytoplasm Cytosol Membrane Cytoplasmic Vesicle
	Molecular Function	Tumor Necrosis Factor-activated Receptor Activity Protein Binding	Integrin Binding Protein Binding Carbohydrate Binding
	Biological Process	Positive Regulation Of Leukocyte Migration Apoptotic Process Signal Transduction Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Apoptotic Process Regulation Of Regulatory T Cell Differentiation Positive Regulation Of Cell Adhesion	Cellular Response To Virus Xenophagy Lymphatic Endothelial Cell Migration
Pathways		TNFs bind their physiological receptors RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)	Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		6 interacting genes: LNX1 TNFSF18 TRAF1 TRAF2 TRAF3 UBQLN2	20 interacting genes: APEH BARD1 CALCOCO2 ERBB2 ITGA3 ITGA4 ITGB1 LRRK2 MEFV MID2 NACC1 NR1D2 TAX1BP1 TRIM17 TRIM22 TRIM23 TRIM49 TRIM5 TRIM6 WBP2
Entrez ID		8784	3964
HPRD ID		04879	09356
Ensembl ID		ENSG00000186891	ENSG00000116977
Uniprot IDs		A0A0R7FDM1 Q9Y5U5	O00214
PDB IDs			2YRO 2YV8 2YXS 3AP4 3AP5 3AP6 3AP7 3AP9 3APB 3OJB 3VKL 3VKM 3VKN 3VKO 4BMB 4BME 4FQZ 4GXL 4HAN 5GZC 5GZD 5GZE 5GZF 5GZG 5T7I 5T7S 5T7T 5T7U 5VWG 6W4Z
Enriched GO Terms of Interacting Partners?
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