LGALS8 and TRIM6

Data Source:
BioGRID (pull down)

		LGALS8	TRIM6
Description		galectin 8	tripartite motif containing 6
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Membrane Cytoplasmic Vesicle	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Integrin Binding Protein Binding Carbohydrate Binding	Protein Binding Transcription Factor Binding Zinc Ion Binding Protein Kinase Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity Protein Tyrosine Kinase Binding
	Biological Process	Cellular Response To Virus Xenophagy Lymphatic Endothelial Cell Migration	Protein Polyubiquitination Positive Regulation Of Defense Response To Virus By Host Positive Regulation Of Cytokine Production Involved In Immune Response Regulation Of Gene Expression Positive Regulation Of Autophagy Negative Regulation Of Gene Expression Positive Regulation Of Peptidyl-threonine Phosphorylation Free Ubiquitin Chain Polymerization Viral Process Protein Ubiquitination Response To Lipopolysaccharide Regulation Of Protein Localization Positive Regulation Of Peptidyl-serine Phosphorylation Cellular Response To Interferon-beta Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Genome Replication Innate Immune Response Negative Regulation Of Transcription, DNA-templated Regulation Of Viral Entry Into Host Cell Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Type I Interferon-mediated Signaling Pathway Cellular Response To Virus Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Transcription Regulatory Region DNA Binding Negative Regulation Of Stem Cell Differentiation
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS		Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)	Cognitive decline rate in late mild cognitive impairment ( 26252872) Malaria ( 31844061)
Interacting Genes		20 interacting genes: APEH BARD1 CALCOCO2 ERBB2 ITGA3 ITGA4 ITGB1 LRRK2 MEFV MID2 NACC1 NR1D2 TAX1BP1 TRIM17 TRIM22 TRIM23 TRIM49 TRIM5 TRIM6 WBP2	4 interacting genes: LGALS3 LGALS8 MYC TRIM5
Entrez ID		3964	117854
HPRD ID		09356	12123
Ensembl ID		ENSG00000116977	ENSG00000121236
Uniprot IDs		O00214	Q9C030
PDB IDs		2YRO 2YV8 2YXS 3AP4 3AP5 3AP6 3AP7 3AP9 3APB 3OJB 3VKL 3VKM 3VKN 3VKO 4BMB 4BME 4FQZ 4GXL 4HAN 5GZC 5GZD 5GZE 5GZF 5GZG 5T7I 5T7S 5T7T 5T7U 5VWG 6W4Z
Enriched GO Terms of Interacting Partners?
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