GPAA1 and PIGU

Data Source:
BioGRID (biochemical)
HPRD (in vivo)

		GPAA1	PIGU
Description		glycosylphosphatidylinositol anchor attachment 1	phosphatidylinositol glycan anchor biosynthesis class U
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Centrosome Cytosol Membrane GPI-anchor Transamidase Complex	Endoplasmic Reticulum Membrane Plasma Membrane Membrane GPI-anchor Transamidase Complex
	Molecular Function	GPI-anchor Transamidase Activity Protein Binding Tubulin Binding GPI Anchor Binding	Protein Binding GPI Anchor Binding
	Biological Process	Proteolysis Protein Retention In ER Lumen Attachment Of GPI Anchor To Protein Protein-containing Complex Assembly	GPI Anchor Biosynthetic Process Attachment Of GPI Anchor To Protein Protein Localization To Cell Surface Regulation Of Receptor Signaling Pathway Via JAK-STAT
Pathways		Attachment of GPI anchor to uPAR	Attachment of GPI anchor to uPAR
Drugs
Diseases
GWAS		Asthma ( 31959851) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Serum metabolite levels ( 23093944)	Bipolar disorder ( 31043756) Brown vs. black hair color ( 30531825) Colorectal cancer or advanced adenoma ( 30510241) Cutaneous melanoma or hair colour ( 32341527) Estimated glomerular filtration rate ( 31152163) Fish- and plant-related diet ( 32066663) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Melanoma ( 28212542) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Smoking status (ever vs never smokers) ( 30643258) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Weight ( 28552196)
Interacting Genes		10 interacting genes: AGTR1 AQP2 EIF3E GNRHR GRIK5 PIGK PIGT PIGU PIN1 PRR13	3 interacting genes: F2RL1 GPAA1 KASH5
Entrez ID		8733	128869
HPRD ID		04334	12250
Ensembl ID		ENSG00000197858	ENSG00000101464
Uniprot IDs		O43292	Q9H490
PDB IDs
Enriched GO Terms of Interacting Partners?
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