GBF1 and ZYG11B

Data Source:
BioGRID (two hybrid)

		GBF1	ZYG11B
Description		golgi brefeldin A resistant guanine nucleotide exchange factor 1	zyg-11 family member B, cell cycle regulator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Trans-Golgi Network Lipid Droplet Cytosol Membrane Cell Leading Edge	Cul2-RING Ubiquitin Ligase Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding	Protein Binding
	Biological Process	Cell Activation Involved In Immune Response Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Post-Golgi Vesicle-mediated Transport Golgi To Endosome Transport Golgi Organization Regulation Of Mitotic Cell Cycle Protein Transport Viral Process Neutrophil Chemotaxis Regulation Of ARF Protein Signal Transduction Protein Localization To Golgi Apparatus Retrograde Transport, Endosome To Golgi COPI Coating Of Golgi Vesicle Regulation Of Catalytic Activity Establishment Of Monopolar Cell Polarity Protein Localization To Endoplasmic Reticulum Exit Site Golgi Disassembly Endoplasmic Reticulum-Golgi Intermediate Compartment Organization Cellular Response To Virus Reactive Oxygen Species Biosynthetic Process Protein Localization To Endoplasmic Reticulum Tubular Network Regulation Of Protein Localization To Cell Surface	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways		trans-Golgi Network Vesicle Budding VxPx cargo-targeting to cilium COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Adult body size ( 32376654) General cognitive ability ( 29844566) Hand grip strength ( 29313844) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) QT interval ( 24952745) Refractive error ( 32231278) Smoking initiation (ever regular vs never regular) ( 30679032) Triglyceride levels ( 32154731) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Monocyte percentage of white cells ( 32888494)
Interacting Genes		7 interacting genes: CDK1 PNPLA2 SRPK2 UBC USO1 YWHAG ZYG11B	4 interacting genes: CUL2 ELOB ELOC GBF1
Entrez ID		8729	79699
HPRD ID		04740	13356
Ensembl ID		ENSG00000107862	ENSG00000162378
Uniprot IDs		A0A669KBG8 Q92538	A8DPD7 B4DK95 Q9C0D3
PDB IDs
Enriched GO Terms of Interacting Partners?
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