URI1 and DMAP1

Data Source:
BioGRID (pull down, affinity chromatography technology, two hybrid)
HPRD (two hybrid, in vivo, in vitro)

		URI1	DMAP1
Description		URI1 prefoldin like chaperone	DNA methyltransferase 1 associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Dendrite	Swr1 Complex Nucleus Nucleoplasm Replication Fork Cytoplasm Cytosol NuA4 Histone Acetyltransferase Complex
	Molecular Function	RNA Polymerase II Complex Binding Chromatin Binding Transcription Corepressor Activity Protein Phosphatase Inhibitor Activity Protein Binding Phosphatase Inhibitor Activity Phosphoprotein Binding	RNA Polymerase II Repressing Transcription Factor Binding Transcription Corepressor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Growth Regulation Of Transcription By RNA Polymerase II Response To Virus Negative Regulation Of Phosphatase Activity Negative Regulation Of Phosphoprotein Phosphatase Activity Cellular Response To Growth Factor Stimulus Cellular Response To Steroid Hormone Stimulus Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II DNA Repair DNA Methylation Regulation Of Growth Positive Regulation Of Protein Import Into Nucleus Histone Exchange Histone H4 Acetylation Histone H2A Acetylation Response To Ethanol Negative Regulation Of Transcription, DNA-templated
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS		Body mass index ( 26426971) Cerebrospinal P-tau181p levels ( 28247064) Diastolic blood pressure ( 27841878) Serum urate levels in chronic kidney disease ( 30181573)	Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: APP ATF7 CIAO1 DMAP1 GTF2F2 ITCH NEDD4 POLR2E RPS6KB1 STAP1	38 interacting genes: ARFIP2 BFSP2 C1orf216 CCHCR1 CDCA7L DAXX DNMT1 EXOC8 GAS8 GINS4 HDAC2 HSF2BP HSPB1 ING1 KRT75 LMNB1 LRSAM1 MIS18A MNAT1 MORF4L1 MRGBP NAP1L2 PFDN1 PIBF1 RGS6 SAAL1 SBK3 SUOX TCEANC TCHP TLK2 TOMM34 TRIM21 TSG101 TSGA10IP TXLNA TXLNB URI1
Entrez ID		8725	55929
HPRD ID		11943	05465
Ensembl ID		ENSG00000105176	ENSG00000178028
Uniprot IDs		O94763	Q9NPF5
PDB IDs			3HM5 4IEJ
Enriched GO Terms of Interacting Partners?
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