URI1 and MEGF8

Data Source:
BioGRID (affinity chromatography technology)

		URI1	MEGF8
Description		URI1 prefoldin like chaperone	multiple EGF like domains 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Dendrite	Nucleus Integral Component Of Membrane Extracellular Exosome
	Molecular Function	RNA Polymerase II Complex Binding Chromatin Binding Transcription Corepressor Activity Protein Phosphatase Inhibitor Activity Protein Binding Phosphatase Inhibitor Activity Phosphoprotein Binding	Calcium Ion Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Growth Regulation Of Transcription By RNA Polymerase II Response To Virus Negative Regulation Of Phosphatase Activity Negative Regulation Of Phosphoprotein Phosphatase Activity Cellular Response To Growth Factor Stimulus Cellular Response To Steroid Hormone Stimulus Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Embryonic Heart Tube Morphogenesis Animal Organ Morphogenesis Tissue Development Regulation Of Gene Expression Embryonic Limb Morphogenesis BMP Signaling Pathway Limb Morphogenesis Cell Migration Involved In Gastrulation Negative Regulation Of Smoothened Signaling Pathway Embryonic Skeletal System Morphogenesis Positive Regulation Of Axon Extension Involved In Axon Guidance Epiboly Involved In Gastrulation With Mouth Forming Second Embryonic Heart Tube Left/right Pattern Formation Left/right Pattern Formation Coronary Vasculature Development Determination Of Heart Left/right Asymmetry Determination Of Digestive Tract Left/right Asymmetry Craniofacial Suture Morphogenesis Fasciculation Of Sensory Neuron Axon
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Cerebrospinal P-tau181p levels ( 28247064) Diastolic blood pressure ( 27841878) Serum urate levels in chronic kidney disease ( 30181573)
Interacting Genes		10 interacting genes: APP ATF7 CIAO1 DMAP1 GTF2F2 ITCH NEDD4 POLR2E RPS6KB1 STAP1	3 interacting genes: ATN1 CACNA1A GFI1B
Entrez ID		8725	1954
HPRD ID		11943	10370
Ensembl ID		ENSG00000105176	ENSG00000105429
Uniprot IDs		O94763	Q7Z7M0
PDB IDs
Enriched GO Terms of Interacting Partners?
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