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MBTPS1 and ZBED8
Data Source:
BioGRID
(two hybrid)
MBTPS1
ZBED8
Description
membrane bound transcription factor peptidase, site 1
zinc finger BED-type containing 8
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Endoplasmic Reticulum Lumen
Endoplasmic Reticulum Membrane
Golgi Apparatus
Golgi Stack
Integral Component Of Membrane
Nucleoplasm
Molecular Function
Serine-type Endopeptidase Activity
Protein Binding
Biological Process
Proteolysis
Protein Import Into Nucleus
Lysosome Organization
Cholesterol Metabolic Process
Endoplasmic Reticulum Unfolded Protein Response
Membrane Protein Intracellular Domain Proteolysis
Response To Endoplasmic Reticulum Stress
ATF6-mediated Unfolded Protein Response
Post-translational Protein Modification
Cellular Protein Metabolic Process
Regulation Of Cholesterol Biosynthetic Process
Regulation Of Vesicle-mediated Transport
Pathways
Regulation of cholesterol biosynthesis by SREBP (SREBF)
ATF6 (ATF6-alpha) activates chaperones
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
CREB3 factors activate genes
CREB3 factors activate genes
Post-translational protein phosphorylation
Assembly of active LPL and LIPC lipase complexes
Drugs
Diseases
GWAS
Iris color (a* coordinate) (
30895295
)
Response to platinum-based neoadjuvant chemotherapy in cervical cancer (
28120872
)
Interacting Genes
10 interacting genes:
ATF6B
BDNF
BIRC3
C11orf58
CANX
CDK2AP2
SPHK1
TNFRSF14
TNFSF11
ZBED8
10 interacting genes:
CEP126
DDIT4L
EED
EEF1G
HSF4
MBTPS1
MEOX2
METTL21A
NAB2
REL
Entrez ID
8720
63920
HPRD ID
04522
17430
Ensembl ID
ENSG00000140943
ENSG00000221886
Uniprot IDs
Q14703
Q8IZ13
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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