DGAT1 and GPAA1

Data Source:
BioGRID (affinity chromatography technology)

		DGAT1	GPAA1
Description		diacylglycerol O-acyltransferase 1	glycosylphosphatidylinositol anchor attachment 1
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Specific Granule Membrane	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Centrosome Cytosol Membrane GPI-anchor Transamidase Complex
	Molecular Function	2-acylglycerol O-acyltransferase Activity Diacylglycerol O-acyltransferase Activity Protein Binding O-acyltransferase Activity Transferase Activity, Transferring Acyl Groups Identical Protein Binding Retinol O-fatty-acyltransferase Activity	GPI-anchor Transamidase Activity Protein Binding Tubulin Binding GPI Anchor Binding
	Biological Process	Monoacylglycerol Biosynthetic Process Triglyceride Metabolic Process Triglyceride Biosynthetic Process Lipid Storage Very-low-density Lipoprotein Particle Assembly Long-chain Fatty-acyl-CoA Metabolic Process Acylglycerol Acyl-chain Remodeling Retinol Metabolic Process Neutrophil Degranulation Diacylglycerol Metabolic Process Fatty Acid Homeostasis	Proteolysis Protein Retention In ER Lumen Attachment Of GPI Anchor To Protein Protein-containing Complex Assembly
Pathways		Acyl chain remodeling of DAG and TAG Neutrophil degranulation Triglyceride biosynthesis	Attachment of GPI anchor to uPAR
Drugs
Diseases
GWAS		Dupuytren's disease ( 28886342)	Asthma ( 31959851) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Serum metabolite levels ( 23093944)
Interacting Genes		3 interacting genes: CCR9 CD1A GABRA4	10 interacting genes: AGTR1 AQP2 EIF3E GNRHR GRIK5 PIGK PIGT PIGU PIN1 PRR13
Entrez ID		8694	8733
HPRD ID		05360	04334
Ensembl ID		ENSG00000185000	ENSG00000197858
Uniprot IDs		O75907	O43292
PDB IDs		6VP0 6VYI 6VZ1
Enriched GO Terms of Interacting Partners?
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