SRSF9 and NOL3

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vitro, in vivo)

		SRSF9	NOL3
Description		serine and arginine rich splicing factor 9	nucleolar protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Nuclear Speck	Nucleolus Mitochondrion Cytosol Membrane Sarcoplasmic Reticulum
	Molecular Function	RNA Binding Protein Binding Protein Domain Specific Binding	RNA Binding Death Receptor Binding Calcium Ion Binding Protein Binding Death Effector Domain Binding Identical Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Caspase Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus Response To Toxic Substance MRNA 3'-end Processing Response To Alkaloid Negative Regulation Of MRNA Splicing, Via Spliceosome	Response To Hypoxia Blood Vessel Remodeling Response To Ischemia MRNA Splice Site Selection RNA Splicing Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Muscle Atrophy Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Response To Injury Involved In Regulation Of Muscle Adaptation Negative Regulation Of Apoptotic Process Protein Complex Oligomerization Negative Regulation Of Necrotic Cell Death Negative Regulation Of Release Of Cytochrome C From Mitochondria Intrinsic Apoptotic Signaling Pathway Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Menopause (age at onset) ( 26414677) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		17 interacting genes: APP C1QBP DUSP11 FUS HABP4 HNRNPUL1 IL7R ITGB5 KHDRBS3 NOL3 RBMX RBMY1A1 RNPS1 SAFB SRPK2 TRA2B YBX1	16 interacting genes: BAX CASP2 CASP8 CSNK2A1 ETNK2 FADD NIF3L1 POT1 SIRPA SRSF9 TERF1 TERF2IP TFPT TINF2 UBQLN2 VASP
Entrez ID		8683	8996
HPRD ID		09053	05572
Ensembl ID		ENSG00000111786	ENSG00000140939
Uniprot IDs		Q13242	O60936 Q5TZN6
PDB IDs			4UZ0
Enriched GO Terms of Interacting Partners?
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