SRSF9 and ITGB5

Data Source:
BioGRID (two hybrid)

		SRSF9	ITGB5
Description		serine and arginine rich splicing factor 9	integrin subunit beta 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Nuclear Speck	Plasma Membrane Focal Adhesion Integrin Complex Cell Surface Integrin Alphav-beta5 Complex Receptor Complex Phagocytic Vesicle Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Protein Domain Specific Binding	Virus Receptor Activity Integrin Binding Protein Binding Signaling Receptor Activity
	Biological Process	Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus Response To Toxic Substance MRNA 3'-end Processing Response To Alkaloid Negative Regulation Of MRNA Splicing, Via Spliceosome	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Muscle Contraction Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell Migration Extracellular Matrix Organization Cell Adhesion Mediated By Integrin Endodermal Cell Differentiation Stress Fiber Assembly Viral Entry Into Host Cell Epithelial Cell-cell Adhesion
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	Cross-presentation of particulate exogenous antigens (phagosomes) Molecules associated with elastic fibres Integrin cell surface interactions Integrin cell surface interactions Syndecan interactions Syndecan interactions ECM proteoglycans Smooth Muscle Contraction
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Menopause (age at onset) ( 26414677) Reticulocyte fraction of red cells ( 32888494)	Airway hyperresponsiveness ( 23984888) Carpal tunnel syndrome ( 30833571) Coronary artery disease ( 28714974) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Diastolic blood pressure ( 27841878) Heel bone mineral density ( 30598549) Mean corpuscular hemoglobin concentration ( 32888494) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		17 interacting genes: APP C1QBP DUSP11 FUS HABP4 HNRNPUL1 IL7R ITGB5 KHDRBS3 NOL3 RBMX RBMY1A1 RNPS1 SAFB SRPK2 TRA2B YBX1	58 interacting genes: ANXA5 APPBP2 CCN1 CYSRT1 DAB1 DAB2 DOK1 EFEMP2 EHMT2 EPS8 EWSR1 FDFT1 FHL2 FHL3 FLNA GAPDH GOLGA2 GON4L ITGA5 ITGAV ITGB3BP KRT31 KRT34 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-2 KRTAP5-7 LTBP1 LTBP3 MTDH MTUS2 MYBPC2 MYO10 NBPF19 NOTCH2NLA NUMB P2RY2 PAK4 PALLD PPARD PTK2 RACK1 SNTA1 SPP1 SRSF9 STAB2 TAF1 TLN1 TNS2 TRIM55 TRIM63 TTN ZBTB17 ZNF655
Entrez ID		8683	3693
HPRD ID		09053	00949
Ensembl ID		ENSG00000111786	ENSG00000082781
Uniprot IDs		Q13242	D3DNA1 L7RT22 P18084
PDB IDs
Enriched GO Terms of Interacting Partners?
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