EIF3G and MIF4GD

Data Source:
BioGRID (two hybrid)

		EIF3G	MIF4GD
Description		eukaryotic translation initiation factor 3 subunit G	MIF4G domain containing
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Perinuclear Region Of Cytoplasm	Nucleolus Golgi Apparatus Cytosol
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding	RNA Binding Protein Binding Protein C-terminus Binding Translation Activator Activity Identical Protein Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Viral Translational Termination-reinitiation	Regulation Of Translational Initiation Positive Regulation Of Translation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS
Interacting Genes		28 interacting genes: ACD AIFM1 APP EIF3A EIF3B EIF3C EIF3D EIF3H EIF3K EIF5 EPB41 FAM9B GADD45G GOLGA2 LMNA MEOX2 METTL3 MIF4GD MPHOSPH6 PALS2 PIN1 PKN2 POT1 PRKAG1 SMN1 SNCA TK1 TRIM14	23 interacting genes: AQP1 ATPAF2 CFAP206 CHCHD2 CRYBA4 CTIF DDIAS DDX19A DDX19B EIF3G ENKD1 EXOSC6 FAM110A HDAC4 HGS HINFP MKRN3 NTAQ1 PDE4DIP PPARG SMARCB1 SVIL UBQLN4
Entrez ID		8666	57409
HPRD ID		04886	10629
Ensembl ID		ENSG00000130811	ENSG00000125457
Uniprot IDs		O75821	A0A0S2Z5K9 A0A0S2Z5S7 A0A0S2Z5T5 A0A3B3IU65 A9UHW6
PDB IDs		2CQ0 2MJC 5K0Y 6YBS 6ZMW
Enriched GO Terms of Interacting Partners?
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