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MIF4GD and EIF3G
Data Source:
BioGRID
(two hybrid)
MIF4GD
EIF3G
Description
MIF4G domain containing
eukaryotic translation initiation factor 3 subunit G
Image
No pdb structure
GO Annotations
Cellular Component
Nucleolus
Golgi Apparatus
Cytosol
Nucleus
Cytoplasm
Cytosol
Eukaryotic Translation Initiation Factor 3 Complex
Eukaryotic 43S Preinitiation Complex
Eukaryotic 48S Preinitiation Complex
Perinuclear Region Of Cytoplasm
Molecular Function
RNA Binding
Protein Binding
Protein C-terminus Binding
Translation Activator Activity
Identical Protein Binding
RNA Binding
Translation Initiation Factor Activity
Protein Binding
Biological Process
Regulation Of Translational Initiation
Positive Regulation Of Translation
Formation Of Cytoplasmic Translation Initiation Complex
Translational Initiation
Viral Translational Termination-reinitiation
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS
Interacting Genes
23 interacting genes:
AQP1
ATPAF2
CFAP206
CHCHD2
CRYBA4
CTIF
DDIAS
DDX19A
DDX19B
EIF3G
ENKD1
EXOSC6
FAM110A
HDAC4
HGS
HINFP
MKRN3
NTAQ1
PDE4DIP
PPARG
SMARCB1
SVIL
UBQLN4
28 interacting genes:
ACD
AIFM1
APP
EIF3A
EIF3B
EIF3C
EIF3D
EIF3H
EIF3K
EIF5
EPB41
FAM9B
GADD45G
GOLGA2
LMNA
MEOX2
METTL3
MIF4GD
MPHOSPH6
PALS2
PIN1
PKN2
POT1
PRKAG1
SMN1
SNCA
TK1
TRIM14
Entrez ID
57409
8666
HPRD ID
10629
04886
Ensembl ID
ENSG00000125457
ENSG00000130811
Uniprot IDs
A0A0S2Z5K9
A0A0S2Z5S7
A0A0S2Z5T5
A0A3B3IU65
A9UHW6
O75821
PDB IDs
2CQ0
2MJC
5K0Y
6YBS
6ZMW
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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