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EIF3A and LINC01554
Data Source:
BioGRID
(unspecified method)
EIF3A
LINC01554
Description
eukaryotic translation initiation factor 3 subunit A
long intergenic non-protein coding RNA 1554
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Eukaryotic Translation Initiation Factor 3 Complex
Microtubule
Postsynaptic Density
Membrane
Eukaryotic 43S Preinitiation Complex
Eukaryotic 48S Preinitiation Complex
Multi-eIF Complex
Eukaryotic Translation Initiation Factor 3 Complex, EIF3e
Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
Molecular Function
RNA Binding
MRNA Binding
Translation Initiation Factor Activity
Structural Molecule Activity
Protein Binding
Receptor Tyrosine Kinase Binding
Biological Process
Formation Of Cytoplasmic Translation Initiation Complex
Translation Reinitiation
Translational Initiation
Negative Regulation Of ERK1 And ERK2 Cascade
IRES-dependent Viral Translational Initiation
Viral Translational Termination-reinitiation
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS
Alcoholic chronic pancreatitis (
28754779
)
Disease progression in age-related macular degeneration (adjusted for baseline) (
29346644
)
Plateletcrit (
32888494
)
Interacting Genes
22 interacting genes:
BBS1
BBS4
BZW2
CACNA1A
EIF3B
EIF3G
EIF3I
EIF3J
EIF4B
EIF4G1
EIF4G2
LAMTOR5
LINC01554
MTNR1B
PAIP1
REL
RNF139
SRPK2
TFIP11
UBC
UPF1
YWHAZ
141 interacting genes:
AARS1
ACADVL
ACIN1
ACTB
ACTG1
ACTN1
ACTN3
ACTR3
ALDOA
ANXA2
ANXA5
ANXA6
APEX1
ARHGAP1
ASS1
ATAD3A
ATIC
ATP5F1A
BZW2
CANX
CCT2
CCT3
CCT4
CCT6A
CCT7
CKAP4
CS
CTPS1
DDX3X
DDX46
DHX9
DNAH2
DNAJA1
DST
DYNC1H1
EDARADD
EEF1G
EEF2
EIF3A
EIF3E
EIF4A2
EIF4B
ENO1
ENO3
EPRS1
ERO1A
G3BP1
G6PD
GANAB
GAPDH
GARS1
GDI2
GPI
GTF2I
HIVEP2
HMCN1
HNRNPF
HSP90AA1
HSP90B1
HSPA1L
HSPA5
HSPA8
HSPA9
HSPD1
HYOU1
IDH1
IPO4
IPO7
IPO9
ITPR2
KARS1
KPNA1
KPNB1
KRT18
KRT7
KRT8
KRT8P3
LRPPRC
MCM7
MSN
MYO18A
NAP1L1
NAP1L4
NCBP1
NCL
NPM1
OLA1
OXCT1
PABPC1
PCBP2
PDIA3
PDIA6
PFAS
PGD
PGK1
PGM1
PHGDH
PKM
PLOD2
PMPCA
POR
PPP2R1A
PSMC1
PSMD2
PSMD7
PTBP1
RDX
RPL6
RPSA
RTCB
RTN4
SARS1
SEPTIN7
SEPTIN9
SERPINH1
SFPQ
SQSTM1
TARS1
TGFBI
THOP1
TKT
TTF2
TUBA1A
TUBA8
TUBB
TUBB2A
TUBB3
TUBB4A
TUBB4B
TUBB6
TUFM
TXNRD1
TYMP
UBA1
VCL
VCP
VIM
VPS35
WARS1
XPO1
XRCC5
Entrez ID
8661
202299
HPRD ID
03618
16896
Ensembl ID
ENSG00000107581
ENSG00000236882
Uniprot IDs
Q14152
PDB IDs
3J8B
3J8C
6YBD
6YBT
6ZMW
6ZON
6ZP4
6ZVJ
7A09
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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