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CBFB and COPRS
Data Source:
BioGRID
(pull down)
CBFB
COPRS
Description
core-binding factor subunit beta
coordinator of PRMT5 and differentiation stimulator
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Membrane
Core-binding Factor Complex
Nucleus
Nucleoplasm
Cytosol
Plasma Membrane
Molecular Function
Transcription Coactivator Activity
Protein Binding
Sequence-specific DNA Binding
Protein Binding
Histone Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Protein Polyubiquitination
Osteoblast Differentiation
Regulation Of Cytokine-mediated Signaling Pathway
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Lymphocyte Differentiation
Myeloid Cell Differentiation
Regulation Of Wnt Signaling Pathway
Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Negative Regulation Of CD4-positive, Alpha-beta T Cell Differentiation
Positive Regulation Of CD8-positive, Alpha-beta T Cell Differentiation
Regulation Of Regulatory T Cell Differentiation
Regulation Of Keratinocyte Differentiation
Regulation Of Myeloid Cell Differentiation
Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Cell Maturation
Regulation Of B Cell Receptor Signaling Pathway
Definitive Hemopoiesis
Regulation Of Hematopoietic Stem Cell Differentiation
Regulation Of Bicellular Tight Junction Assembly
Muscle Organ Development
Histone H4-R3 Methylation
Pathways
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)
Transcriptional regulation by RUNX2
Transcriptional regulation by RUNX2
RUNX1 regulates estrogen receptor mediated transcription
Regulation of RUNX1 Expression and Activity
RUNX1 regulates expression of components of tight junctions
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
RUNX1 regulates transcription of genes involved in differentiation of HSCs
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
RUNX1 regulates transcription of genes involved in BCR signaling
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
RUNX1 regulates transcription of genes involved in interleukin signaling
RUNX1 regulates transcription of genes involved in WNT signaling
Regulation of RUNX2 expression and activity
Regulation of RUNX2 expression and activity
RUNX2 regulates osteoblast differentiation
RUNX2 regulates osteoblast differentiation
RUNX2 regulates chondrocyte maturation
RUNX2 regulates bone development
RUNX2 regulates genes involved in cell migration
RUNX2 regulates genes involved in cell migration
RUNX2 regulates genes involved in differentiation of myeloid cells
Regulation of RUNX3 expression and activity
RUNX3 Regulates Immune Response and Cell Migration
RUNX3 Regulates Immune Response and Cell Migration
RUNX3 regulates RUNX1-mediated transcription
RUNX3 regulates p14-ARF
Estrogen-dependent gene expression
Transcriptional regulation of granulopoiesis
RMTs methylate histone arginines
Drugs
Diseases
GWAS
Mean corpuscular hemoglobin (
27863252
)
Coronary artery disease (
33020668
)
High chromosomal aberration frequency (chromosome type) (
31586183
)
High chromosomal aberration frequency (chromosome type) in genotoxic compound exposure (
31586183
)
Urinary albumin excretion (
32277301
)
Interacting Genes
9 interacting genes:
CBFA2T2
CHGB
CHRM5
COPRS
RAB2A
RNF7
RUNX1
RUNX2
RUNX3
4 interacting genes:
CBFB
H3-4
H4-16
RUNX1
Entrez ID
865
55352
HPRD ID
00418
13675
Ensembl ID
ENSG00000067955
ENSG00000172301
Uniprot IDs
A0A024R6X2
Q13951
H9KV77
Q9NQ92
PDB IDs
1CL3
1E50
1H9D
4N9F
6NIL
6P59
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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