CAV2 and DRD1

Data Source:
HPRD (in vitro)

		CAV2	DRD1
Description		caveolin 2	dopamine receptor D1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Acrosomal Membrane Caveolar Macromolecular Signaling Complex Nucleus Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Caveola Focal Adhesion Transport Vesicle Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Cytoplasmic Vesicle Protein-containing Complex Sarcolemma Membrane Raft Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Cilium Dendritic Spine Ciliary Membrane Non-motile Cilium
	Molecular Function	Protein Binding Protein Kinase Binding Protein-macromolecule Adaptor Activity Protein Homodimerization Activity Protein Heterodimerization Activity Molecular Adaptor Activity Scaffold Protein Binding	Dopamine Neurotransmitter Receptor Activity, Coupled Via Gs G Protein-coupled Receptor Activity Dopamine Neurotransmitter Receptor Activity Protein Binding Dopamine Binding
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Positive Regulation Of Endothelial Cell Proliferation Vesicle Fusion Mitochondrion Organization Endoplasmic Reticulum Organization Regulation Of Mitotic Nuclear Division Insulin Receptor Signaling Pathway Vesicle Organization Receptor-mediated Endocytosis Of Virus By Host Cell Cell Differentiation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of MAPK Cascade Positive Regulation Of GTPase Activity Positive Regulation By Host Of Viral Release From Host Cell Positive Regulation By Host Of Viral Process Vesicle Docking Skeletal Muscle Fiber Development Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Dopamine Receptor Signaling Pathway Caveola Assembly Basement Membrane Organization	Synaptic Transmission, Dopaminergic G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Dopamine Receptor Signaling Pathway Synapse Assembly Mating Behavior Adult Walking Behavior Visual Learning Positive Regulation Of Gene Expression Transmission Of Nerve Impulse Cerebral Cortex GABAergic Interneuron Migration Positive Regulation Of Cell Migration Vasodilation Dopamine Metabolic Process Response To Drug Positive Regulation Of Potassium Ion Transport Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Synaptic Transmission, Glutamatergic Prepulse Inhibition Phospholipase C-activating Dopamine Receptor Signaling Pathway Cellular Response To Catecholamine Stimulus Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Cellular Response To Dopamine
Pathways		Extra-nuclear estrogen signaling	Dopamine receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			Ziprasidone Cabergoline Cabergoline Olanzapine Olanzapine Methylergometrine Clozapine Phenylpropanolamine Loxapine Loxapine Imipramine Chlorpromazine Chlorpromazine Haloperidol Triflupromazine Amoxapine Lamotrigine Cinnarizine Lisuride Fluphenazine Thioridazine Ergotamine Apomorphine Paroxetine Trimipramine Risperidone Fenoldopam Minaprine Perphenazine Flupentixol Dopamine Dopamine Carphenazine Ergoloid mesylate Pergolide Bromocriptine Quetiapine Levodopa Aripiprazole Chlorprothixene Paliperidone Methotrimeprazine Periciazine Acepromazine Pipotiazine Thioproperazine Thiothixene Zuclopenthixol Iloperidone Rotigotine Lumateperone Mianserin Asenapine Quinagolide Zotepine Pipamperone Dihydro-alpha-ergocryptine Epicriptine Pipradrol Tetrahydropalmatine Dihydrexidine Dihydroergocristine Aripiprazole lauroxil
Diseases
GWAS		Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Atrial fibrillation ( 30061737 29892015) Glaucoma ( 31959993 30054594) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 29891935 25173105 20835238) Heart rate increase in response to exercise ( 29497042) Heart rate response to exercise ( 29769521) Heart rate response to recovery post exercise ( 29769521) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Intraocular pressure ( 29617998 25173106 31798171 29785010 31959993 30054594 28073927) Ischemic stroke (cardioembolic) ( 29531354) P wave duration ( 28794112) PR interval ( 29127183 30046033 32439900 20062060 25035420) Refractive error ( 32231278) TPE interval (resting) ( 32386560)	Cadmium levels ( 26025379) Chin dimples ( 27182965) Falling risk ( 32999390) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Treatment response for severe sepsis ( 22310353) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		12 interacting genes: CAV1 CSNK2A1 DNAJA1 DRD1 EGFR FLOT2 GOLGB1 MALL NCK1 RASA1 SDCBP SRC	16 interacting genes: ADA ADORA1 CALY CAV2 COPG1 COPG2 DNAJC14 DRD3 EPB41L2 FLNA GHSR GRIN1 HRH3 PDCD6IP PRKACA VPS35
Entrez ID		858	1812
HPRD ID		03029	00538
Ensembl ID		ENSG00000105971	ENSG00000184845
Uniprot IDs		P51636 Q53X57	P21728
PDB IDs			1OZ5
Enriched GO Terms of Interacting Partners?
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