FBF1 and VPS37B

Data Source:
BioGRID (two hybrid)

		FBF1	VPS37B
Description		Fas binding factor 1	VPS37B subunit of ESCRT-I
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Centrosome Centriole Cytosol Ciliary Basal Body Apical Junction Complex Keratin Filament Ciliary Transition Fiber	ESCRT I Complex Cytoplasm Endosome Plasma Membrane Endosome Membrane Midbody Late Endosome Membrane Intracellular Membrane-bounded Organelle Host Cell Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Calcium-dependent Protein Binding
	Biological Process	Apical Junction Assembly Cilium Assembly Establishment Of Epithelial Cell Polarity Ciliary Basal Body-plasma Membrane Docking	Protein Targeting To Membrane Protein Targeting To Vacuole Endosomal Transport Macroautophagy Viral Life Cycle Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Intracellular Transport Of Virus Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Viral Budding Via Host ESCRT Complex
Pathways		Anchoring of the basal body to the plasma membrane	Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) White matter hyperintensity burden ( 25663218)	Tourette syndrome ( 30818990)
Interacting Genes		49 interacting genes: ABI3 ACCS APP BLZF1 CALCOCO2 CCDC102B CCDC85B CEP55 CEP63 CINP CLK1 DEUP1 DGCR6 FAS FBXL12 GATA1 GCC1 GOLGA2 HIF1AN IFT20 IKZF3 KRT13 KRT31 KRT40 MEOX2 MID2 MIPOL1 PNMA1 RBPMS RHOXF2 SSX2IP SUMO1 TADA2A TASOR2 TCEA2 TEX11 TLE5 TMCC2 TRAF1 TRAF2 TRIM23 TRIM27 TRIM29 TRIM54 TSGA10 TTC32 TUBGCP4 USHBP1 VPS37B	25 interacting genes: BAG3 BYSL CDC73 DCUN1D1 ENKD1 ERCC1 EXOC8 FBF1 GORASP2 HGS KDM1A LNX1 NCK2 OSTF1 PRKAA1 PRKAA2 QARS1 SH3YL1 SMARCD1 SORBS3 TLE5 TSG101 UBASH3A UBASH3B VPS28
Entrez ID		85302	79720
HPRD ID		10948	07794
Ensembl ID		ENSG00000188878	ENSG00000139722
Uniprot IDs		Q8TES7	A0A024RBU0 Q9H9H4
PDB IDs			6VME
Enriched GO Terms of Interacting Partners?
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